Transfer factor induced delayed hypersensitivity in X-linked combined immunodeficiency

Randall M. Goldblum, Ralph A. Lord, Elton Dupree, Arthur G. Weinberg, Armond S. Goldman

Research output: Contribution to journalArticle

15 Scopus citations


A 5-month-old male with an X-linked combined immunodeficiency was treated with transfer factor. Consequently, lymphocyte stimulation to phytohemagglutinin and Candida as well as delayed hypersensitivity to candida and 2,4-dinitrochlorobenzene developed and persisted for 4 weeks. When cellular immunity diminished, the patient succumbed to Pneumocystis carinii and cytomegalovirus infections. Because of the transfer of cellular immunity in this case, further trials of transfer factor are indicated when histocompatible bone marrow is not available for patients with combined immunodeficiency.

Original languageEnglish (US)
Pages (from-to)297-305
Number of pages9
JournalCellular Immunology
Issue number2
StatePublished - 1973


ASJC Scopus subject areas

  • Cell Biology
  • Immunology

Cite this

Goldblum, R. M., Lord, R. A., Dupree, E., Weinberg, A. G., & Goldman, A. S. (1973). Transfer factor induced delayed hypersensitivity in X-linked combined immunodeficiency. Cellular Immunology, 9(2), 297-305.