Abstract
Infection of hamster embryonic fibroblast (HEF) cells with UV-irradiated human CMV resulted in appearance of transformed clones. The established cell line (87-TRH-5) when inoculated subcutaneously induced tumour in newborn hamsters. The 87-TRH-5 cell line and the cell lines (87-TRH-5-Tsc1, 87-TRH-5-Tsc2, 87TRH-5-Tsc3) developed from the induced tumour, proved to bear CMV-spcific cytoplasmic and surface antigens. Demonstration of infectious CMV or MCV-specific nuclear antigen in 87-THR-5-cells has failed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 269-275 |
| Number of pages | 7 |
| Journal | Acta microbiologica Academiae Scientiarum Hungaricae |
| Volume | 25 |
| Issue number | 4 |
| State | Published - 1978 |
| Externally published | Yes |
ASJC Scopus subject areas
- General Medicine