Abstract
Biopsies from volunteers challenged with Cryptosporidium parvum were examined for transforming growth factor β1 (TGF-β1). None of the prechallenge biopsies exhibited TGF-β. Seven of 12 volunteers with oocyst shedding expressed TGF-β versus 2 of 13 volunteers without detected oocysts. The association of TGF-β expression with oocyst excretion and the timing of symptoms suggests that TGF-β mediates intestinal healing.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 5405-5407 |
| Number of pages | 3 |
| Journal | Infection and immunity |
| Volume | 68 |
| Issue number | 9 |
| DOIs | |
| State | Published - 2000 |
| Externally published | Yes |
ASJC Scopus subject areas
- Parasitology
- Microbiology
- Immunology
- Infectious Diseases