Transmission cycles, host range, evolution and emergence of arboviral disease

Research output: Contribution to journalArticle

360 Scopus citations


Many pandemics have been attributed to the ability of some RNA viruses to change their host range to include humans. Here, we review the mechanisms of disease emergence that are related to the host-range specificity of selected mosquito-borne alphaviruses and flaviviruses. We discuss viruses of medical importance, including Venezuelan equine and Japanese encephalitis viruses, dengue viruses and West Nile viruses.

Original languageEnglish (US)
Pages (from-to)789-801
Number of pages13
JournalNature Reviews Microbiology
Issue number10
StatePublished - Oct 2004


ASJC Scopus subject areas

  • Microbiology

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