Transmission of oropouche virus from man to hamster by the midge Culicoides paraensis

Francisco P. Pinheiro, Amelia P A Travassos Da Rosa, Maria L C Gomes, James LeDuc, Alfred L. Hoch

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Oropouche virus (arbovirus family Bunyaviridae, Simbu serological group) was experimentally transmitted from man to hamster by the bite of the midge Culicoides paraensis. Infection rates and transmission rates were determined after the midge had engorged on patients with viremia. The threshold titer necessary to enable infection or transmission by the midges was approximately 5.3 log10 of the median lethal dose of the virus in suckling mice per milliliter of blood. Transmission was achieved 6 to 12 days after C. paraensis had taken the infective blood meal. This represents conclusive evidence of transmission of an arbovirus of public health importance to man by a member of the Ceratopogonidae family.

Original languageEnglish (US)
Pages (from-to)1251-1253
Number of pages3
JournalScience
Volume215
Issue number4537
StatePublished - 1982
Externally publishedYes

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Ceratopogonidae
Arboviruses
Infectious Disease Transmission
Cricetinae
Bunyaviridae
Viruses
Viremia
Bites and Stings
Meals
Public Health

ASJC Scopus subject areas

  • General

Cite this

Pinheiro, F. P., Travassos Da Rosa, A. P. A., Gomes, M. L. C., LeDuc, J., & Hoch, A. L. (1982). Transmission of oropouche virus from man to hamster by the midge Culicoides paraensis. Science, 215(4537), 1251-1253.

Transmission of oropouche virus from man to hamster by the midge Culicoides paraensis. / Pinheiro, Francisco P.; Travassos Da Rosa, Amelia P A; Gomes, Maria L C; LeDuc, James; Hoch, Alfred L.

In: Science, Vol. 215, No. 4537, 1982, p. 1251-1253.

Research output: Contribution to journalArticle

Pinheiro, FP, Travassos Da Rosa, APA, Gomes, MLC, LeDuc, J & Hoch, AL 1982, 'Transmission of oropouche virus from man to hamster by the midge Culicoides paraensis', Science, vol. 215, no. 4537, pp. 1251-1253.
Pinheiro FP, Travassos Da Rosa APA, Gomes MLC, LeDuc J, Hoch AL. Transmission of oropouche virus from man to hamster by the midge Culicoides paraensis. Science. 1982;215(4537):1251-1253.
Pinheiro, Francisco P. ; Travassos Da Rosa, Amelia P A ; Gomes, Maria L C ; LeDuc, James ; Hoch, Alfred L. / Transmission of oropouche virus from man to hamster by the midge Culicoides paraensis. In: Science. 1982 ; Vol. 215, No. 4537. pp. 1251-1253.
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