TY - JOUR
T1 - Treadmill exercise tests in persons with Parkinson’s disease
T2 - responses and disease severity
AU - Bryant, Mon S.
AU - Jackson, George R.
AU - Hou, Jyhgong Gabriel
AU - Protas, Elizabeth J.
N1 - Funding Information:
The study was partially supported by the National Institute of Health, R01 HD051844. Dr. Bryant received research support from the Department of Veterans Affairs, Rehabilitation Research and Development Service, CDA-2 Grant No. B7878 W (Bryant MS), the Michael E DeBakey VA Medical Center, Houston, TX. Financial disclosure statements were obtained, and no conflicts of interest were reported by the authors or by any individuals in control of the content of this article.
Publisher Copyright:
© 2015, Springer International Publishing Switzerland.
PY - 2016/10/1
Y1 - 2016/10/1
N2 - Background and aims: There is a paucity of information on cardiovascular responses with regard to the disease stage of Parkinson’s disease (PD) when using an exercise test. Our purpose was to examine whether cardiovascular responses to the treadmill exercise test differed among persons with PD who have different disease severity. Methods: Forty-five subjects with PD were studied (34 men and 11 women). The subjects underwent a treadmill exercise test using a modified Bruce protocol. Resting heart rate (HR), resting blood pressure (BP), maximal HR, maximal BP, exercise duration, maximum percentage HR and METs achieved after the treadmill exercise test were studied. Results: Seventeen subjects were in Hoehn and Yahr Staging Scale (HY) 2, 16 were in HY 2.5, and 12 were in HY 3. HR increased significantly in all three stages. Systolic BP increased significantly in the HY 2 and 2.5, but not the HY 3. Diastolic BP did not change in any stage. Resting HR was lower in the HY 2 compared to the HY 3 and resting systolic BP was higher in HY 2 compared to the HY 2.5. The three HY stages were not different in exercise duration, HR and BP responses, maximum percentage HR achieved, and METs achieved. Fatigue was a primary reason to discontinue the test. There were no fall incidents in any of the tests. Conclusions: Cardiovascular responses to the treadmill exercise test did not vary with disease severity. Treadmill exercise tests were safe to perform in persons with PD.
AB - Background and aims: There is a paucity of information on cardiovascular responses with regard to the disease stage of Parkinson’s disease (PD) when using an exercise test. Our purpose was to examine whether cardiovascular responses to the treadmill exercise test differed among persons with PD who have different disease severity. Methods: Forty-five subjects with PD were studied (34 men and 11 women). The subjects underwent a treadmill exercise test using a modified Bruce protocol. Resting heart rate (HR), resting blood pressure (BP), maximal HR, maximal BP, exercise duration, maximum percentage HR and METs achieved after the treadmill exercise test were studied. Results: Seventeen subjects were in Hoehn and Yahr Staging Scale (HY) 2, 16 were in HY 2.5, and 12 were in HY 3. HR increased significantly in all three stages. Systolic BP increased significantly in the HY 2 and 2.5, but not the HY 3. Diastolic BP did not change in any stage. Resting HR was lower in the HY 2 compared to the HY 3 and resting systolic BP was higher in HY 2 compared to the HY 2.5. The three HY stages were not different in exercise duration, HR and BP responses, maximum percentage HR achieved, and METs achieved. Fatigue was a primary reason to discontinue the test. There were no fall incidents in any of the tests. Conclusions: Cardiovascular responses to the treadmill exercise test did not vary with disease severity. Treadmill exercise tests were safe to perform in persons with PD.
KW - Cardiovascular response
KW - Modified Bruce protocol
KW - Parkinson’s disease
KW - Treadmill exercise test
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U2 - 10.1007/s40520-015-0498-x
DO - 10.1007/s40520-015-0498-x
M3 - Article
C2 - 26590841
AN - SCOPUS:84947788051
SN - 1594-0667
VL - 28
SP - 1009
EP - 1014
JO - Aging Clinical and Experimental Research
JF - Aging Clinical and Experimental Research
IS - 5
ER -