Treatment of large intracranial aneurysms using the Woven EndoBridge (WEB): a propensity score-matched analysis

Basel Musmar; Hamza Adel Salim; Nimer Adeeb; Assala Aslan; Bahaa Aljeradat; Jose Danilo Bengzon Diestro; Rachel M. McLellan; Oktay Algin; Sherief Ghozy; Mahmoud Dibas; Sovann V. Lay; Adrien Guenego; Leonardo Renieri; Nicole M. Cancelliere; Joseph Carnevale; Guillaume Saliou; Panagiotis Mastorakos; Kareem El Naamani; Eimad Shotar; Kevin Premat; Markus Möhlenbruch; Michael Kral; Justin E. Vranic; Charlotte Chung; Mohamed M. Salem; Ivan Lylyk; Paul M. Foreman; Jay A. Vachhani; Hamza Shaikh; Vedran Župančić; Muhammad U. Hafeez; Joshua Catapano; Muhammad Waqas; Vincent M. Tutino; Mohamed K. Ibrahim; Marwa A. Mohammed; M. Ozgur Ozates; Giyas Ayberk; James D. Rabinov; Yifan Ren; Clemens M. Schirmer; Mariangela Piano; Anna L. Kühn; Caterina Michelozzi; Stéphanie Elens; Robert M. Starke; Ameer Hassan; Mark Ogilvie; Anh Nguyen; Jesse Jones; Waleed Brinjikji; Marie T. Nawka; Marios Psychogios; Christian Ulfert; Julian Spears; Brian T. Jankowitz; Jan Karl Burkhardt; Ricardo A. Domingo; Thien Huynh; Juan Carlos Martinez-Gutierrez; Muhammed Amir Essibayi; Sunil A. Sheth; Gary Spiegel; Rabih Tawk; Boris Lubicz; Pietro Panni; Ajit S. Puri; Guglielmo Pero; Erez Nossek; Eytan Raz; Monika Killer-Oberfalzer; Christoph J. Griessenauer; Hamed Asadi; Adnan Siddiqui; Allan Brook; David Altschul; Andrew F. Ducruet; Felipe C. Albuquerque; Robert W. Regenhardt; Christopher J. Stapleton; Peter Kan; Vladimir Kalousek; Pedro Lylyk; Srikanth Boddu; Jared Knopman; Mohammad A. Aziz-Sultan; Stavropoula I. Tjoumakaris; Frédéric Clarençon; Nicola Limbucci; Hugo H. Cuellar-Saenz; Pascal M. Jabbour; Vitor Mendes Pereira; Aman B. Patel; Adam A. Dmytriw

doi:10.1007/s10143-024-02527-5

Treatment of large intracranial aneurysms using the Woven EndoBridge (WEB): a propensity score-matched analysis

Basel Musmar, Hamza Adel Salim, Nimer Adeeb, Assala Aslan, Bahaa Aljeradat, Jose Danilo Bengzon Diestro, Rachel M. McLellan, Oktay Algin, Sherief Ghozy, Mahmoud Dibas, Sovann V. Lay, Adrien Guenego, Leonardo Renieri, Nicole M. Cancelliere, Joseph Carnevale, Guillaume Saliou, Panagiotis Mastorakos, Kareem El Naamani, Eimad Shotar, Kevin PrematMarkus Möhlenbruch, Michael Kral, Justin E. Vranic, Charlotte Chung, Mohamed M. Salem, Ivan Lylyk, Paul M. Foreman, Jay A. Vachhani, Hamza Shaikh, Vedran Župančić, Muhammad U. Hafeez, Joshua Catapano, Muhammad Waqas, Vincent M. Tutino, Mohamed K. Ibrahim, Marwa A. Mohammed, M. Ozgur Ozates, Giyas Ayberk, James D. Rabinov, Yifan Ren, Clemens M. Schirmer, Mariangela Piano, Anna L. Kühn, Caterina Michelozzi, Stéphanie Elens, Robert M. Starke, Ameer Hassan, Mark Ogilvie, Anh Nguyen, Jesse Jones, Waleed Brinjikji, Marie T. Nawka, Marios Psychogios, Christian Ulfert, Julian Spears, Brian T. Jankowitz, Jan Karl Burkhardt, Ricardo A. Domingo, Thien Huynh, Juan Carlos Martinez-Gutierrez, Muhammed Amir Essibayi, Sunil A. Sheth, Gary Spiegel, Rabih Tawk, Boris Lubicz, Pietro Panni, Ajit S. Puri, Guglielmo Pero, Erez Nossek, Eytan Raz, Monika Killer-Oberfalzer, Christoph J. Griessenauer, Hamed Asadi, Adnan Siddiqui, Allan Brook, David Altschul, Andrew F. Ducruet, Felipe C. Albuquerque, Robert W. Regenhardt, Christopher J. Stapleton, Peter Kan, Vladimir Kalousek, Pedro Lylyk, Srikanth Boddu, Jared Knopman, Mohammad A. Aziz-Sultan, Stavropoula I. Tjoumakaris, Frédéric Clarençon, Nicola Limbucci, Hugo H. Cuellar-Saenz, Pascal M. Jabbour, Vitor Mendes Pereira, Aman B. Patel, Adam A. Dmytriw

Research output: Contribution to journal › Article › peer-review

Abstract

The Woven EndoBridge (WEB) device is primarily used for treating wide-neck intracranial bifurcation aneurysms under 10 mm. Limited data exists on its efficacy for large aneurysms. We aim to assess angiographic and clinical outcomes of the WEB device in treating large versus small aneurysms. We conducted a retrospective review of the WorldWide WEB Consortium database, from 2011 to 2022, across 30 academic institutions globally. Propensity score matching (PSM) was employed to compare small and large aneurysms on baseline characteristics. A total of 898 patients were included. There was no significant difference observed in clinical presentations, smoking status, pretreatment mRS, presence of multiple aneurysms, bifurcation location, or prior treatment between the two groups. After PSM, 302 matched pairs showed significantly lower last follow-up adequate occlusion rates (81% vs 90%, p = 0.006) and higher retreatment rates (12% vs 3.6%, p < 0.001) in the large aneurysm group. These findings may inform treatment decisions and patient counseling. Future studies are needed to further explore this area.

Original language	English (US)
Article number	374
Journal	Neurosurgical Review
Volume	47
Issue number	1
DOIs	https://doi.org/10.1007/s10143-024-02527-5
State	Published - Dec 2024
Externally published	Yes

Keywords

Aneurysms
Intracranial
Treatment
WEB
Woven EndoBridge

ASJC Scopus subject areas

Surgery
Clinical Neurology

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10.1007/s10143-024-02527-5

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Musmar, B., Salim, H. A., Adeeb, N., Aslan, A., Aljeradat, B., Diestro, J. D. B., McLellan, R. M., Algin, O., Ghozy, S., Dibas, M., Lay, S. V., Guenego, A., Renieri, L., Cancelliere, N. M., Carnevale, J., Saliou, G., Mastorakos, P., El Naamani, K., Shotar, E., ... Dmytriw, A. A. (2024). Treatment of large intracranial aneurysms using the Woven EndoBridge (WEB): a propensity score-matched analysis. Neurosurgical Review, 47(1), Article 374. https://doi.org/10.1007/s10143-024-02527-5

Musmar, B, Salim, HA, Adeeb, N, Aslan, A, Aljeradat, B, Diestro, JDB, McLellan, RM, Algin, O, Ghozy, S, Dibas, M, Lay, SV, Guenego, A, Renieri, L, Cancelliere, NM, Carnevale, J, Saliou, G, Mastorakos, P, El Naamani, K, Shotar, E, Premat, K, Möhlenbruch, M, Kral, M, Vranic, JE, Chung, C, Salem, MM, Lylyk, I, Foreman, PM, Vachhani, JA, Shaikh, H, Župančić, V, Hafeez, MU, Catapano, J, Waqas, M, Tutino, VM, Ibrahim, MK, Mohammed, MA, Ozates, MO, Ayberk, G, Rabinov, JD, Ren, Y, Schirmer, CM, Piano, M, Kühn, AL, Michelozzi, C, Elens, S, Starke, RM, Hassan, A, Ogilvie, M, Nguyen, A, Jones, J, Brinjikji, W, Nawka, MT, Psychogios, M, Ulfert, C, Spears, J, Jankowitz, BT, Burkhardt, JK, Domingo, RA, Huynh, T, Martinez-Gutierrez, JC, Essibayi, MA, Sheth, SA, Spiegel, G, Tawk, R, Lubicz, B, Panni, P, Puri, AS, Pero, G, Nossek, E, Raz, E, Killer-Oberfalzer, M, Griessenauer, CJ, Asadi, H, Siddiqui, A, Brook, A, Altschul, D, Ducruet, AF, Albuquerque, FC, Regenhardt, RW, Stapleton, CJ, Kan, P, Kalousek, V, Lylyk, P, Boddu, S, Knopman, J, Aziz-Sultan, MA, Tjoumakaris, SI, Clarençon, F, Limbucci, N, Cuellar-Saenz, HH, Jabbour, PM, Pereira, VM, Patel, AB & Dmytriw, AA 2024, 'Treatment of large intracranial aneurysms using the Woven EndoBridge (WEB): a propensity score-matched analysis', Neurosurgical Review, vol. 47, no. 1, 374. https://doi.org/10.1007/s10143-024-02527-5

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title = "Treatment of large intracranial aneurysms using the Woven EndoBridge (WEB): a propensity score-matched analysis",

abstract = "The Woven EndoBridge (WEB) device is primarily used for treating wide-neck intracranial bifurcation aneurysms under 10 mm. Limited data exists on its efficacy for large aneurysms. We aim to assess angiographic and clinical outcomes of the WEB device in treating large versus small aneurysms. We conducted a retrospective review of the WorldWide WEB Consortium database, from 2011 to 2022, across 30 academic institutions globally. Propensity score matching (PSM) was employed to compare small and large aneurysms on baseline characteristics. A total of 898 patients were included. There was no significant difference observed in clinical presentations, smoking status, pretreatment mRS, presence of multiple aneurysms, bifurcation location, or prior treatment between the two groups. After PSM, 302 matched pairs showed significantly lower last follow-up adequate occlusion rates (81% vs 90%, p = 0.006) and higher retreatment rates (12% vs 3.6%, p < 0.001) in the large aneurysm group. These findings may inform treatment decisions and patient counseling. Future studies are needed to further explore this area.",

keywords = "Aneurysms, Intracranial, Treatment, WEB, Woven EndoBridge",

author = "Basel Musmar and Salim, {Hamza Adel} and Nimer Adeeb and Assala Aslan and Bahaa Aljeradat and Diestro, {Jose Danilo Bengzon} and McLellan, {Rachel M.} and Oktay Algin and Sherief Ghozy and Mahmoud Dibas and Lay, {Sovann V.} and Adrien Guenego and Leonardo Renieri and Cancelliere, {Nicole M.} and Joseph Carnevale and Guillaume Saliou and Panagiotis Mastorakos and {El Naamani}, Kareem and Eimad Shotar and Kevin Premat and Markus M{\"o}hlenbruch and Michael Kral and Vranic, {Justin E.} and Charlotte Chung and Salem, {Mohamed M.} and Ivan Lylyk and Foreman, {Paul M.} and Vachhani, {Jay A.} and Hamza Shaikh and Vedran {\v Z}upan{\v c}i{\'c} and Hafeez, {Muhammad U.} and Joshua Catapano and Muhammad Waqas and Tutino, {Vincent M.} and Ibrahim, {Mohamed K.} and Mohammed, {Marwa A.} and Ozates, {M. Ozgur} and Giyas Ayberk and Rabinov, {James D.} and Yifan Ren and Schirmer, {Clemens M.} and Mariangela Piano and K{\"u}hn, {Anna L.} and Caterina Michelozzi and St{\'e}phanie Elens and Starke, {Robert M.} and Ameer Hassan and Mark Ogilvie and Anh Nguyen and Jesse Jones and Waleed Brinjikji and Nawka, {Marie T.} and Marios Psychogios and Christian Ulfert and Julian Spears and Jankowitz, {Brian T.} and Burkhardt, {Jan Karl} and Domingo, {Ricardo A.} and Thien Huynh and Martinez-Gutierrez, {Juan Carlos} and Essibayi, {Muhammed Amir} and Sheth, {Sunil A.} and Gary Spiegel and Rabih Tawk and Boris Lubicz and Pietro Panni and Puri, {Ajit S.} and Guglielmo Pero and Erez Nossek and Eytan Raz and Monika Killer-Oberfalzer and Griessenauer, {Christoph J.} and Hamed Asadi and Adnan Siddiqui and Allan Brook and David Altschul and Ducruet, {Andrew F.} and Albuquerque, {Felipe C.} and Regenhardt, {Robert W.} and Stapleton, {Christopher J.} and Peter Kan and Vladimir Kalousek and Pedro Lylyk and Srikanth Boddu and Jared Knopman and Aziz-Sultan, {Mohammad A.} and Tjoumakaris, {Stavropoula I.} and Fr{\'e}d{\'e}ric Claren{\c c}on and Nicola Limbucci and Cuellar-Saenz, {Hugo H.} and Jabbour, {Pascal M.} and Pereira, {Vitor Mendes} and Patel, {Aman B.} and Dmytriw, {Adam A.}",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2024.",

year = "2024",

month = dec,

doi = "10.1007/s10143-024-02527-5",

language = "English (US)",

volume = "47",

journal = "Neurosurgical Review",

issn = "0344-5607",

publisher = "Springer Verlag",

number = "1",

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TY - JOUR

T1 - Treatment of large intracranial aneurysms using the Woven EndoBridge (WEB)

T2 - a propensity score-matched analysis

AU - Musmar, Basel

AU - Salim, Hamza Adel

AU - Adeeb, Nimer

AU - Aslan, Assala

AU - Aljeradat, Bahaa

AU - Diestro, Jose Danilo Bengzon

AU - McLellan, Rachel M.

AU - Algin, Oktay

AU - Ghozy, Sherief

AU - Dibas, Mahmoud

AU - Lay, Sovann V.

AU - Guenego, Adrien

AU - Renieri, Leonardo

AU - Cancelliere, Nicole M.

AU - Carnevale, Joseph

AU - Saliou, Guillaume

AU - Mastorakos, Panagiotis

AU - El Naamani, Kareem

AU - Shotar, Eimad

AU - Premat, Kevin

AU - Möhlenbruch, Markus

AU - Kral, Michael

AU - Vranic, Justin E.

AU - Chung, Charlotte

AU - Salem, Mohamed M.

AU - Lylyk, Ivan

AU - Foreman, Paul M.

AU - Vachhani, Jay A.

AU - Shaikh, Hamza

AU - Župančić, Vedran

AU - Hafeez, Muhammad U.

AU - Catapano, Joshua

AU - Waqas, Muhammad

AU - Tutino, Vincent M.

AU - Ibrahim, Mohamed K.

AU - Mohammed, Marwa A.

AU - Ozates, M. Ozgur

AU - Ayberk, Giyas

AU - Rabinov, James D.

AU - Ren, Yifan

AU - Schirmer, Clemens M.

AU - Piano, Mariangela

AU - Kühn, Anna L.

AU - Michelozzi, Caterina

AU - Elens, Stéphanie

AU - Starke, Robert M.

AU - Hassan, Ameer

AU - Ogilvie, Mark

AU - Nguyen, Anh

AU - Jones, Jesse

AU - Brinjikji, Waleed

AU - Nawka, Marie T.

AU - Psychogios, Marios

AU - Ulfert, Christian

AU - Spears, Julian

AU - Jankowitz, Brian T.

AU - Burkhardt, Jan Karl

AU - Domingo, Ricardo A.

AU - Huynh, Thien

AU - Martinez-Gutierrez, Juan Carlos

AU - Essibayi, Muhammed Amir

AU - Sheth, Sunil A.

AU - Spiegel, Gary

AU - Tawk, Rabih

AU - Lubicz, Boris

AU - Panni, Pietro

AU - Puri, Ajit S.

AU - Pero, Guglielmo

AU - Nossek, Erez

AU - Raz, Eytan

AU - Killer-Oberfalzer, Monika

AU - Griessenauer, Christoph J.

AU - Asadi, Hamed

AU - Siddiqui, Adnan

AU - Brook, Allan

AU - Altschul, David

AU - Ducruet, Andrew F.

AU - Albuquerque, Felipe C.

AU - Regenhardt, Robert W.

AU - Stapleton, Christopher J.

AU - Kan, Peter

AU - Kalousek, Vladimir

AU - Lylyk, Pedro

AU - Boddu, Srikanth

AU - Knopman, Jared

AU - Aziz-Sultan, Mohammad A.

AU - Tjoumakaris, Stavropoula I.

AU - Clarençon, Frédéric

AU - Limbucci, Nicola

AU - Cuellar-Saenz, Hugo H.

AU - Jabbour, Pascal M.

AU - Pereira, Vitor Mendes

AU - Patel, Aman B.

AU - Dmytriw, Adam A.

PY - 2024/12

Y1 - 2024/12

N2 - The Woven EndoBridge (WEB) device is primarily used for treating wide-neck intracranial bifurcation aneurysms under 10 mm. Limited data exists on its efficacy for large aneurysms. We aim to assess angiographic and clinical outcomes of the WEB device in treating large versus small aneurysms. We conducted a retrospective review of the WorldWide WEB Consortium database, from 2011 to 2022, across 30 academic institutions globally. Propensity score matching (PSM) was employed to compare small and large aneurysms on baseline characteristics. A total of 898 patients were included. There was no significant difference observed in clinical presentations, smoking status, pretreatment mRS, presence of multiple aneurysms, bifurcation location, or prior treatment between the two groups. After PSM, 302 matched pairs showed significantly lower last follow-up adequate occlusion rates (81% vs 90%, p = 0.006) and higher retreatment rates (12% vs 3.6%, p < 0.001) in the large aneurysm group. These findings may inform treatment decisions and patient counseling. Future studies are needed to further explore this area.

AB - The Woven EndoBridge (WEB) device is primarily used for treating wide-neck intracranial bifurcation aneurysms under 10 mm. Limited data exists on its efficacy for large aneurysms. We aim to assess angiographic and clinical outcomes of the WEB device in treating large versus small aneurysms. We conducted a retrospective review of the WorldWide WEB Consortium database, from 2011 to 2022, across 30 academic institutions globally. Propensity score matching (PSM) was employed to compare small and large aneurysms on baseline characteristics. A total of 898 patients were included. There was no significant difference observed in clinical presentations, smoking status, pretreatment mRS, presence of multiple aneurysms, bifurcation location, or prior treatment between the two groups. After PSM, 302 matched pairs showed significantly lower last follow-up adequate occlusion rates (81% vs 90%, p = 0.006) and higher retreatment rates (12% vs 3.6%, p < 0.001) in the large aneurysm group. These findings may inform treatment decisions and patient counseling. Future studies are needed to further explore this area.

KW - Aneurysms

KW - Intracranial

KW - Treatment

KW - WEB

KW - Woven EndoBridge

UR - http://www.scopus.com/inward/record.url?scp=85200053925&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85200053925&partnerID=8YFLogxK

U2 - 10.1007/s10143-024-02527-5

DO - 10.1007/s10143-024-02527-5

M3 - Article

C2 - 39083214

AN - SCOPUS:85200053925

SN - 0344-5607

VL - 47

JO - Neurosurgical Review

JF - Neurosurgical Review

IS - 1

M1 - 374

ER -

Treatment of large intracranial aneurysms using the Woven EndoBridge (WEB): a propensity score-matched analysis

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Keywords

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