Triple hybrids of steroids, spiroketals, and oligopeptides as new biomolecular chimeras

Abhisek Banerjee; Eduard Sergienko; Stefan Vasile; Vineet Gupta; Kristiina Vuori; Peter Wipf

doi:10.1021/ol802247m

Triple hybrids of steroids, spiroketals, and oligopeptides as new biomolecular chimeras

Abhisek Banerjee
, Eduard Sergienko
, Stefan Vasile
, Vineet Gupta
, Kristiina Vuori
, Peter Wipf

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

An oxidative enol ether rearrangement was the key methodology in the construction of steroid-spiroketal-RGD peptides. Biological studies demonstrated potent integrin CD11b/CD18 antagonistic effects.

Original language	English (US)
Pages (from-to)	65-68
Number of pages	4
Journal	Organic Letters
Volume	11
Issue number	1
DOIs	https://doi.org/10.1021/ol802247m
State	Published - Jan 1 2009
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol802247m

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title = "Triple hybrids of steroids, spiroketals, and oligopeptides as new biomolecular chimeras",

abstract = "An oxidative enol ether rearrangement was the key methodology in the construction of steroid-spiroketal-RGD peptides. Biological studies demonstrated potent integrin CD11b/CD18 antagonistic effects.",

author = "Abhisek Banerjee and Eduard Sergienko and Stefan Vasile and Vineet Gupta and Kristiina Vuori and Peter Wipf",

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T1 - Triple hybrids of steroids, spiroketals, and oligopeptides as new biomolecular chimeras

AU - Banerjee, Abhisek

AU - Sergienko, Eduard

AU - Vasile, Stefan

AU - Gupta, Vineet

AU - Vuori, Kristiina

AU - Wipf, Peter

PY - 2009/1/1

Y1 - 2009/1/1

N2 - An oxidative enol ether rearrangement was the key methodology in the construction of steroid-spiroketal-RGD peptides. Biological studies demonstrated potent integrin CD11b/CD18 antagonistic effects.

AB - An oxidative enol ether rearrangement was the key methodology in the construction of steroid-spiroketal-RGD peptides. Biological studies demonstrated potent integrin CD11b/CD18 antagonistic effects.

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UR - https://www.scopus.com/pages/publications/59649094100#tab=citedBy

U2 - 10.1021/ol802247m

DO - 10.1021/ol802247m

M3 - Article

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ER -

Triple hybrids of steroids, spiroketals, and oligopeptides as new biomolecular chimeras

Abstract

ASJC Scopus subject areas

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