Trophoblastic embolization during molar evacuation

Central hemodynamic observations

Gary Hankins, G. D. Wendel, Russell Snyder, F. G. Cunningham

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

We evaluated prospectively the extent of trophoblastic embolization and its central hemodynamic effects during and after evacuation of large molar pregnancies in six women. A pulmonary artery catheter was inserted to obtain hemodynamic measurements as well as to obtain blood samples to identify trophoblasts before, during, and six hours after evacuation. Small numbers of both multinucleated giant cells and of large mononuclear cells with abundant cytoplasm were identified in the buffy coat of blood, aspirated in two cases before evacuation and for all six cases, during evacuation. There were no significant changes in heart rate or mean systemic arterial, pulmonary arterial, central venous, and pulmonary capillary wedge pressures; or cardiac output, stroke volume, and pulmonary or systemic vascular resistance when preevacuation preanesthetic values were compared with those six hours after evacuation. However, significant decreases in heart rate, mean arterial pressure, and pulmonary vascular resistance were observed during evacuation, which returned to preevacuation levels by completion of anesthesia.

Original languageEnglish (US)
Pages (from-to)368-372
Number of pages5
JournalObstetrics and Gynecology
Volume69
Issue number3 I
StatePublished - 1987
Externally publishedYes

Fingerprint

Vascular Resistance
Hemodynamics
Blood Buffy Coat
Heart Rate
Hydatidiform Mole
Pulmonary Wedge Pressure
Trophoblasts
Giant Cells
Cardiac Output
Stroke Volume
Pulmonary Artery
Arterial Pressure
Cytoplasm
Catheters
Anesthesia
Lung

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Trophoblastic embolization during molar evacuation : Central hemodynamic observations. / Hankins, Gary; Wendel, G. D.; Snyder, Russell; Cunningham, F. G.

In: Obstetrics and Gynecology, Vol. 69, No. 3 I, 1987, p. 368-372.

Research output: Contribution to journalArticle

Hankins, G, Wendel, GD, Snyder, R & Cunningham, FG 1987, 'Trophoblastic embolization during molar evacuation: Central hemodynamic observations', Obstetrics and Gynecology, vol. 69, no. 3 I, pp. 368-372.
Hankins, Gary ; Wendel, G. D. ; Snyder, Russell ; Cunningham, F. G. / Trophoblastic embolization during molar evacuation : Central hemodynamic observations. In: Obstetrics and Gynecology. 1987 ; Vol. 69, No. 3 I. pp. 368-372.
@article{9a577b3c2a02498784f2de1ab69999bb,
title = "Trophoblastic embolization during molar evacuation: Central hemodynamic observations",
abstract = "We evaluated prospectively the extent of trophoblastic embolization and its central hemodynamic effects during and after evacuation of large molar pregnancies in six women. A pulmonary artery catheter was inserted to obtain hemodynamic measurements as well as to obtain blood samples to identify trophoblasts before, during, and six hours after evacuation. Small numbers of both multinucleated giant cells and of large mononuclear cells with abundant cytoplasm were identified in the buffy coat of blood, aspirated in two cases before evacuation and for all six cases, during evacuation. There were no significant changes in heart rate or mean systemic arterial, pulmonary arterial, central venous, and pulmonary capillary wedge pressures; or cardiac output, stroke volume, and pulmonary or systemic vascular resistance when preevacuation preanesthetic values were compared with those six hours after evacuation. However, significant decreases in heart rate, mean arterial pressure, and pulmonary vascular resistance were observed during evacuation, which returned to preevacuation levels by completion of anesthesia.",
author = "Gary Hankins and Wendel, {G. D.} and Russell Snyder and Cunningham, {F. G.}",
year = "1987",
language = "English (US)",
volume = "69",
pages = "368--372",
journal = "Obstetrics and Gynecology",
issn = "0029-7844",
publisher = "Lippincott Williams and Wilkins",
number = "3 I",

}

TY - JOUR

T1 - Trophoblastic embolization during molar evacuation

T2 - Central hemodynamic observations

AU - Hankins, Gary

AU - Wendel, G. D.

AU - Snyder, Russell

AU - Cunningham, F. G.

PY - 1987

Y1 - 1987

N2 - We evaluated prospectively the extent of trophoblastic embolization and its central hemodynamic effects during and after evacuation of large molar pregnancies in six women. A pulmonary artery catheter was inserted to obtain hemodynamic measurements as well as to obtain blood samples to identify trophoblasts before, during, and six hours after evacuation. Small numbers of both multinucleated giant cells and of large mononuclear cells with abundant cytoplasm were identified in the buffy coat of blood, aspirated in two cases before evacuation and for all six cases, during evacuation. There were no significant changes in heart rate or mean systemic arterial, pulmonary arterial, central venous, and pulmonary capillary wedge pressures; or cardiac output, stroke volume, and pulmonary or systemic vascular resistance when preevacuation preanesthetic values were compared with those six hours after evacuation. However, significant decreases in heart rate, mean arterial pressure, and pulmonary vascular resistance were observed during evacuation, which returned to preevacuation levels by completion of anesthesia.

AB - We evaluated prospectively the extent of trophoblastic embolization and its central hemodynamic effects during and after evacuation of large molar pregnancies in six women. A pulmonary artery catheter was inserted to obtain hemodynamic measurements as well as to obtain blood samples to identify trophoblasts before, during, and six hours after evacuation. Small numbers of both multinucleated giant cells and of large mononuclear cells with abundant cytoplasm were identified in the buffy coat of blood, aspirated in two cases before evacuation and for all six cases, during evacuation. There were no significant changes in heart rate or mean systemic arterial, pulmonary arterial, central venous, and pulmonary capillary wedge pressures; or cardiac output, stroke volume, and pulmonary or systemic vascular resistance when preevacuation preanesthetic values were compared with those six hours after evacuation. However, significant decreases in heart rate, mean arterial pressure, and pulmonary vascular resistance were observed during evacuation, which returned to preevacuation levels by completion of anesthesia.

UR - http://www.scopus.com/inward/record.url?scp=0023158740&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023158740&partnerID=8YFLogxK

M3 - Article

VL - 69

SP - 368

EP - 372

JO - Obstetrics and Gynecology

JF - Obstetrics and Gynecology

SN - 0029-7844

IS - 3 I

ER -