Tuftsin and tuftsin analogs: Biology, synthesis and design theory

Kenji Nishioka, John McMurray, Fahad Al Obeidi, Bernard Pettitt

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

We have reviewed aspects of the medicinal chemistry of Tuftsin. Biochemical and clinical aspects including physiology and assays are briefly accounted for. Structure-activity relationships found in the literature provide a link between the synthetic/design strategies and the biological response. Directed rational design and synthetic techniques are reviewed for both tuftsin and its analogs.

Original languageEnglish (US)
Pages (from-to)153-166
Number of pages14
JournalCurrent Medicinal Chemistry
Volume3
Issue number3
StatePublished - 1996
Externally publishedYes

Fingerprint

Tuftsin
Pharmaceutical Chemistry
Physiology
Structure-Activity Relationship
Assays

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Organic Chemistry
  • Pharmacology

Cite this

Tuftsin and tuftsin analogs : Biology, synthesis and design theory. / Nishioka, Kenji; McMurray, John; Al Obeidi, Fahad; Pettitt, Bernard.

In: Current Medicinal Chemistry, Vol. 3, No. 3, 1996, p. 153-166.

Research output: Contribution to journalArticle

Nishioka, K, McMurray, J, Al Obeidi, F & Pettitt, B 1996, 'Tuftsin and tuftsin analogs: Biology, synthesis and design theory', Current Medicinal Chemistry, vol. 3, no. 3, pp. 153-166.
Nishioka, Kenji ; McMurray, John ; Al Obeidi, Fahad ; Pettitt, Bernard. / Tuftsin and tuftsin analogs : Biology, synthesis and design theory. In: Current Medicinal Chemistry. 1996 ; Vol. 3, No. 3. pp. 153-166.
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