Abstract
We have reviewed aspects of the medicinal chemistry of Tuftsin. Biochemical and clinical aspects including physiology and assays are briefly accounted for. Structure-activity relationships found in the literature provide a link between the synthetic/design strategies and the biological response. Directed rational design and synthetic techniques are reviewed for both tuftsin and its analogs.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 153-166 |
| Number of pages | 14 |
| Journal | Current Medicinal Chemistry |
| Volume | 3 |
| Issue number | 3 |
| State | Published - 1996 |
| Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Molecular Medicine
- Pharmacology
- Drug Discovery
- Organic Chemistry