Twenty four hour integrated concentrations of progesterone, 17 hydroxyprogesterone and cortisol in normal male subjects

J. P. Gutai, Walter Meyer, A. A. Kowarski, C. J. Migeon

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

The 24 h integrated concentrations of progesterone, 17 hydroxyprogesterone (17 OHP) and cortisol were determined in 5 male subjects ranging in age from 25 to 36 years. Using a nonthrombogenic catheter and a constant withdrawal pump, blood was collected for a period of 24 h in 30 min aliquots. All five subjects had similar 24 h integrated concentrations of cortisol (9.2 ± 5.4). One subject had elevated 24 h integrated concentrations of progesterone (55.2 ± 18.7) and 17 OHP (352 ± 122) when compared to the mean integrated concentrations (progesterone: 24.9 ± 4.7; 17 OHP: 109 ± 33) of the 4 other subjects. The 30 min integrated concentrations showed a diurnal variation for both 17 OHP and cortisol but not for progesterone. The best correlation between cortisol and 17 OHP occurred when the concentrations of cortisol were correlated with the concentrations of 17 OHP 90 or 120 min earlier. No significant correlation occurred between cortisol and progesterone.

Original languageEnglish (US)
Pages (from-to)116-120
Number of pages5
JournalJournal of Clinical Endocrinology and Metabolism
Volume44
Issue number1
StatePublished - 1977
Externally publishedYes

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17-alpha-Hydroxyprogesterone
Progesterone
Hydrocortisone
Catheters
Blood
Pumps

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology, Diabetes and Metabolism

Cite this

Twenty four hour integrated concentrations of progesterone, 17 hydroxyprogesterone and cortisol in normal male subjects. / Gutai, J. P.; Meyer, Walter; Kowarski, A. A.; Migeon, C. J.

In: Journal of Clinical Endocrinology and Metabolism, Vol. 44, No. 1, 1977, p. 116-120.

Research output: Contribution to journalArticle

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