Twin pregnancies discordant for single umbilical artery

Benjamin D. Byers, George Saade, Hassan Harirah

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

OBJECTIVE: To evaluate the perinatal outcomes in twin pregnancies discordant for single umbilical artery (SUA). STUDY DESIGN: This was a retrospective cohort study. Our database was searched for all cases of twin gestation and SUA from 1997-2009. We reviewed all the maternal and neonatal records and placental pathology reports. The outcomes of the SUA fetuses were compared to that of their cotwins with a 3-vessel cord (3VC). Paired t test and χ2 tests were used for statistical analyses. RESULTS: We identified 29 cases of twin pregnancies discordant for SUA out of 60,989 ultrasound patients. There were no differences in the prevalence of coexisting anomalies (34% vs. 21%, p=0.38) between the SUA fetus and the 3VC fetus. The SUA fetus was found to have significantly lower mean birth weight (1,784±765 g vs. 2,053±668 g, p=0.001), 1-minute Apgar score (6.83 ± 1.89 vs. 7.62 ± 1.18, p = 0.037), and umbilical artery cord pH (7.27±0.06 vs. 7.31±0.07, p=0.001). The SUA fetus was smaller 79% of the time (p<0.0001). The SUA fetus achieved a significantly lower percentile (12.77%±21.8 vs. 32.00%±27.56, p=0.002) when calculating the customized growth potential. CONCLUSION: The fetus affected by an SUA in a twin gestation has impaired fetal growth and neonatal outcomes when compared to its 3VC counterpart.

Original languageEnglish (US)
Pages (from-to)241-245
Number of pages5
JournalJournal of Reproductive Medicine
Volume58
Issue number5-6
StatePublished - Jun 2013

Fingerprint

Single Umbilical Artery
Twin Pregnancy
Fetus
Pregnancy
Umbilical Arteries
Apgar Score
Umbilical Cord
Fetal Development
Birth Weight
Cohort Studies
Retrospective Studies
Mothers
Databases

Keywords

  • Fetal growth
  • Single umbilical artery
  • Twins

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Reproductive Medicine

Cite this

Twin pregnancies discordant for single umbilical artery. / Byers, Benjamin D.; Saade, George; Harirah, Hassan.

In: Journal of Reproductive Medicine, Vol. 58, No. 5-6, 06.2013, p. 241-245.

Research output: Contribution to journalArticle

@article{24a1b4deec824ec2808e8146800cea9e,
title = "Twin pregnancies discordant for single umbilical artery",
abstract = "OBJECTIVE: To evaluate the perinatal outcomes in twin pregnancies discordant for single umbilical artery (SUA). STUDY DESIGN: This was a retrospective cohort study. Our database was searched for all cases of twin gestation and SUA from 1997-2009. We reviewed all the maternal and neonatal records and placental pathology reports. The outcomes of the SUA fetuses were compared to that of their cotwins with a 3-vessel cord (3VC). Paired t test and χ2 tests were used for statistical analyses. RESULTS: We identified 29 cases of twin pregnancies discordant for SUA out of 60,989 ultrasound patients. There were no differences in the prevalence of coexisting anomalies (34{\%} vs. 21{\%}, p=0.38) between the SUA fetus and the 3VC fetus. The SUA fetus was found to have significantly lower mean birth weight (1,784±765 g vs. 2,053±668 g, p=0.001), 1-minute Apgar score (6.83 ± 1.89 vs. 7.62 ± 1.18, p = 0.037), and umbilical artery cord pH (7.27±0.06 vs. 7.31±0.07, p=0.001). The SUA fetus was smaller 79{\%} of the time (p<0.0001). The SUA fetus achieved a significantly lower percentile (12.77{\%}±21.8 vs. 32.00{\%}±27.56, p=0.002) when calculating the customized growth potential. CONCLUSION: The fetus affected by an SUA in a twin gestation has impaired fetal growth and neonatal outcomes when compared to its 3VC counterpart.",
keywords = "Fetal growth, Single umbilical artery, Twins",
author = "Byers, {Benjamin D.} and George Saade and Hassan Harirah",
year = "2013",
month = "6",
language = "English (US)",
volume = "58",
pages = "241--245",
journal = "The Journal of reproductive medicine",
issn = "0024-7758",
publisher = "Donna Kessel",
number = "5-6",

}

TY - JOUR

T1 - Twin pregnancies discordant for single umbilical artery

AU - Byers, Benjamin D.

AU - Saade, George

AU - Harirah, Hassan

PY - 2013/6

Y1 - 2013/6

N2 - OBJECTIVE: To evaluate the perinatal outcomes in twin pregnancies discordant for single umbilical artery (SUA). STUDY DESIGN: This was a retrospective cohort study. Our database was searched for all cases of twin gestation and SUA from 1997-2009. We reviewed all the maternal and neonatal records and placental pathology reports. The outcomes of the SUA fetuses were compared to that of their cotwins with a 3-vessel cord (3VC). Paired t test and χ2 tests were used for statistical analyses. RESULTS: We identified 29 cases of twin pregnancies discordant for SUA out of 60,989 ultrasound patients. There were no differences in the prevalence of coexisting anomalies (34% vs. 21%, p=0.38) between the SUA fetus and the 3VC fetus. The SUA fetus was found to have significantly lower mean birth weight (1,784±765 g vs. 2,053±668 g, p=0.001), 1-minute Apgar score (6.83 ± 1.89 vs. 7.62 ± 1.18, p = 0.037), and umbilical artery cord pH (7.27±0.06 vs. 7.31±0.07, p=0.001). The SUA fetus was smaller 79% of the time (p<0.0001). The SUA fetus achieved a significantly lower percentile (12.77%±21.8 vs. 32.00%±27.56, p=0.002) when calculating the customized growth potential. CONCLUSION: The fetus affected by an SUA in a twin gestation has impaired fetal growth and neonatal outcomes when compared to its 3VC counterpart.

AB - OBJECTIVE: To evaluate the perinatal outcomes in twin pregnancies discordant for single umbilical artery (SUA). STUDY DESIGN: This was a retrospective cohort study. Our database was searched for all cases of twin gestation and SUA from 1997-2009. We reviewed all the maternal and neonatal records and placental pathology reports. The outcomes of the SUA fetuses were compared to that of their cotwins with a 3-vessel cord (3VC). Paired t test and χ2 tests were used for statistical analyses. RESULTS: We identified 29 cases of twin pregnancies discordant for SUA out of 60,989 ultrasound patients. There were no differences in the prevalence of coexisting anomalies (34% vs. 21%, p=0.38) between the SUA fetus and the 3VC fetus. The SUA fetus was found to have significantly lower mean birth weight (1,784±765 g vs. 2,053±668 g, p=0.001), 1-minute Apgar score (6.83 ± 1.89 vs. 7.62 ± 1.18, p = 0.037), and umbilical artery cord pH (7.27±0.06 vs. 7.31±0.07, p=0.001). The SUA fetus was smaller 79% of the time (p<0.0001). The SUA fetus achieved a significantly lower percentile (12.77%±21.8 vs. 32.00%±27.56, p=0.002) when calculating the customized growth potential. CONCLUSION: The fetus affected by an SUA in a twin gestation has impaired fetal growth and neonatal outcomes when compared to its 3VC counterpart.

KW - Fetal growth

KW - Single umbilical artery

KW - Twins

UR - http://www.scopus.com/inward/record.url?scp=84877982867&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84877982867&partnerID=8YFLogxK

M3 - Article

VL - 58

SP - 241

EP - 245

JO - The Journal of reproductive medicine

JF - The Journal of reproductive medicine

SN - 0024-7758

IS - 5-6

ER -