Two-dimensional opto-acoustic tomography transducer array and image reconstruction algorithm

Alexander A. Oraevsky, Valeri G. Andreev, Alexander A. Karabutov, Rinat Esenaliev

Research output: Chapter in Book/Report/Conference proceedingChapter

67 Citations (Scopus)

Abstract

Opto-acoustic tomography (OAT) utilizes laser pulses to create acoustic sources in tissue and wide-band detection of pressure profiles for the image reconstruction. A new laser optoacoustic imaging system (LOIS) for breast cancer detection and two-dimensional visualization is described. A Q-switched Nd:YAG laser was used for generation of opto-acoustic profiles in phantoms and tissues in vitro. Acoustic pulses were detected by a 12 element linear array of piezoelectric transducers. Each transducer was made of 0.5-mm thick PVDF slabs with dimensions of 4.3 mm×12.5 mm. Signal-to-noise ratio was calculated and the sensitivity of optoacoustic system was evaluated. The axial (in-depth) resolution and the lateral resolution of the system were determined. The axial resolution of the receiving array was limited by its frequency band and was estimated to be approximately 1 mm. The lateral resolution was about 2.5 times the lateral dimension of the `tumor' and defined by the finite aperture of the array and relatively large size of the single transducer. The time of full data acquisition was limited by the time allowed in clinical procedure of about 5-10 minutes. The procedure of signal processing is described. It includes high-pass signal filtering, compensation for acoustic diffraction, detection of the irradiated surface position and rejection of the reverberating signal. Radial back-projection algorithm for image reconstruction was developed and included in the computer code. Two-dimensional opto-acoustic images of simulated spheres and objects inside tissue phantoms are presented. The contrast of these images and limits of detection and localization of deeply embedded tumors are discussed.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
PublisherSociety of Photo-Optical Instrumentation Engineers
Pages256-267
Number of pages12
Volume3601
StatePublished - 1999
EventProceedings of the 1999 Laser-Tissue Interaction X: Photochemical, Photothermal, and Photomechanical - San Jose, CA, USA
Duration: Jan 24 1999Jan 27 1999

Other

OtherProceedings of the 1999 Laser-Tissue Interaction X: Photochemical, Photothermal, and Photomechanical
CitySan Jose, CA, USA
Period1/24/991/27/99

Fingerprint

image reconstruction
Image reconstruction
Tomography
Transducers
transducers
tomography
Acoustics
acoustics
Photoacoustic effect
Tissue
Tumors
tumors
Piezoelectric transducers
Lasers
piezoelectric transducers
linear arrays
Q switched lasers
profiles
pulses
breast

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Oraevsky, A. A., Andreev, V. G., Karabutov, A. A., & Esenaliev, R. (1999). Two-dimensional opto-acoustic tomography transducer array and image reconstruction algorithm. In Proceedings of SPIE - The International Society for Optical Engineering (Vol. 3601, pp. 256-267). Society of Photo-Optical Instrumentation Engineers.

Two-dimensional opto-acoustic tomography transducer array and image reconstruction algorithm. / Oraevsky, Alexander A.; Andreev, Valeri G.; Karabutov, Alexander A.; Esenaliev, Rinat.

Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3601 Society of Photo-Optical Instrumentation Engineers, 1999. p. 256-267.

Research output: Chapter in Book/Report/Conference proceedingChapter

Oraevsky, AA, Andreev, VG, Karabutov, AA & Esenaliev, R 1999, Two-dimensional opto-acoustic tomography transducer array and image reconstruction algorithm. in Proceedings of SPIE - The International Society for Optical Engineering. vol. 3601, Society of Photo-Optical Instrumentation Engineers, pp. 256-267, Proceedings of the 1999 Laser-Tissue Interaction X: Photochemical, Photothermal, and Photomechanical, San Jose, CA, USA, 1/24/99.
Oraevsky AA, Andreev VG, Karabutov AA, Esenaliev R. Two-dimensional opto-acoustic tomography transducer array and image reconstruction algorithm. In Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3601. Society of Photo-Optical Instrumentation Engineers. 1999. p. 256-267
Oraevsky, Alexander A. ; Andreev, Valeri G. ; Karabutov, Alexander A. ; Esenaliev, Rinat. / Two-dimensional opto-acoustic tomography transducer array and image reconstruction algorithm. Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3601 Society of Photo-Optical Instrumentation Engineers, 1999. pp. 256-267
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