Two-wavelength optoacoustic technique for accurate, noninvasive, and continuous measurement of blood oxygenation

Y. Y. Petrov, D. S. Prough, D. Hilbert, D. J. Deyo, M. Motamedi, R. O. Esenaliev

Research output: Contribution to journalConference articlepeer-review

2 Scopus citations


Noninvasive monitoring of blood oxygenation (oxyhemoglobin saturation) offers great promise in the management of life-threatening illnesses including traumatic brain injury. We proposed and built a two-wavelength optoacoustic system to accurately and noninvasively monitor blood oxygenation in veins. The system includes nanosecond Nd:YAG and Alexandrite lasers and a specially designed optoacoustic probe. We tested the system in vitro in sheep blood with experimentally varied oxygenation and total hemoglobin concentration. Our results demonstrated that the system is capable of blood oxygenation measurements with high accuracy despite variation of total hemoglobin concentration. These results suggest that the two-wavelength optoacoustic technique can be used for patients with different or changing hemoglobin concentrations as may happen during infusion of blood-free fluids or as a consequence of hemorrhage.

Original languageEnglish (US)
Pages (from-to)2287-2288
Number of pages2
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
StatePublished - 2002
EventProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States
Duration: Oct 23 2002Oct 26 2002


  • Hemoglobin
  • Noninvasive monitoring
  • Optics
  • Tissue

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics


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