Two-wavelength optoacoustic technique for accurate, noninvasive, and continuous measurement of blood oxygenation

Y. Y. Petrov, Donald Prough, D. Hilbert, D. J. Deyo, Massoud Motamedi, Rinat Esenaliev

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Noninvasive monitoring of blood oxygenation (oxyhemoglobin saturation) offers great promise in the management of life-threatening illnesses including traumatic brain injury. We proposed and built a two-wavelength optoacoustic system to accurately and noninvasively monitor blood oxygenation in veins. The system includes nanosecond Nd:YAG and Alexandrite lasers and a specially designed optoacoustic probe. We tested the system in vitro in sheep blood with experimentally varied oxygenation and total hemoglobin concentration. Our results demonstrated that the system is capable of blood oxygenation measurements with high accuracy despite variation of total hemoglobin concentration. These results suggest that the two-wavelength optoacoustic technique can be used for patients with different or changing hemoglobin concentrations as may happen during infusion of blood-free fluids or as a consequence of hemorrhage.

Original languageEnglish (US)
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Pages2287-2288
Number of pages2
Volume3
StatePublished - 2002
EventProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States
Duration: Oct 23 2002Oct 26 2002

Other

OtherProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS)
CountryUnited States
CityHouston, TX
Period10/23/0210/26/02

Fingerprint

Oxygenation
Photoacoustic effect
Blood
Hemoglobin
Wavelength
Hemoglobins
Oxyhemoglobins
Brain
Fluids
Lasers
Monitoring

Keywords

  • Hemoglobin
  • Noninvasive monitoring
  • Optics
  • Tissue

ASJC Scopus subject areas

  • Bioengineering

Cite this

Petrov, Y. Y., Prough, D., Hilbert, D., Deyo, D. J., Motamedi, M., & Esenaliev, R. (2002). Two-wavelength optoacoustic technique for accurate, noninvasive, and continuous measurement of blood oxygenation. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol. 3, pp. 2287-2288)

Two-wavelength optoacoustic technique for accurate, noninvasive, and continuous measurement of blood oxygenation. / Petrov, Y. Y.; Prough, Donald; Hilbert, D.; Deyo, D. J.; Motamedi, Massoud; Esenaliev, Rinat.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 3 2002. p. 2287-2288.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Petrov, YY, Prough, D, Hilbert, D, Deyo, DJ, Motamedi, M & Esenaliev, R 2002, Two-wavelength optoacoustic technique for accurate, noninvasive, and continuous measurement of blood oxygenation. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. vol. 3, pp. 2287-2288, Proceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS), Houston, TX, United States, 10/23/02.
Petrov YY, Prough D, Hilbert D, Deyo DJ, Motamedi M, Esenaliev R. Two-wavelength optoacoustic technique for accurate, noninvasive, and continuous measurement of blood oxygenation. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 3. 2002. p. 2287-2288
Petrov, Y. Y. ; Prough, Donald ; Hilbert, D. ; Deyo, D. J. ; Motamedi, Massoud ; Esenaliev, Rinat. / Two-wavelength optoacoustic technique for accurate, noninvasive, and continuous measurement of blood oxygenation. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 3 2002. pp. 2287-2288
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