Ultrasonographic measurement of crown-rump length in high-order multifetal pregnancies

George Saade, G. Gray, M. A. Belfort, R. J. Carpenter, K. J. Moise

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The objective of the study was to evaluate the crown-rump length (CRL) in high-order multifetal pregnancies (three or more fetuses). The records of patients who underwent multifetal pregnancy reduction were reviewed. The following parameters were defined: the mean CRL (CRL(MEAN)) and the difference between the largest and smallest CRL (CRL(RANGE)) for each pregnancy. CRL(MEAN) was plotted versus gestational age (GA) and the line of best fit was derived. The residual for each CRL (CRL(RES)) was calculated by subtracting the value predicted by the regression line from the individual CRL (CRL(IND)). Regression lines for single tons with confirmed GA from four previously reported studies were used for comparison. A total of 82 patients were included (29 triplets, 38 quadruplets and 15 quintuplets; mean GA 10.7 ± 0.78 weeks). CRL(MEAN) correlated with GA (CRL(MEAN) = 38.88 - 8.78 (GA) + 0.82 (GA)2; R = 0.83; R2 = 0.70). This second-degree polynomial remained within the range for singletons. No significant differences in maternal age, GA and CRL(MEAN) were noted between the patients with different numbers of fetuses. The median CRL(RANGE) was largest in quintuplets, followed by quadruplets and triplets. The CRL(RANGE) correlated poorly with GA. The mean CRL in multifetal pregnancies Increases with GA similarly to that in singletons. The variability of individual measurements increases with the number of fetuses and CRLs are lower in quintuplets.

Original languageEnglish (US)
Pages (from-to)438-444
Number of pages7
JournalUltrasound in Obstetrics and Gynecology
Volume11
Issue number6
DOIs
StatePublished - 1998

Fingerprint

Crown-Rump Length
pregnancy
Pregnancy
Gestational Age
fetuses
Quintuplets
regression analysis
Fetus
polynomials
Multifetal Pregnancy Reduction
Maternal Age

Keywords

  • Crown-rump length
  • Multifetal pregnancy
  • Ultrasound

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Reproductive Medicine
  • Acoustics and Ultrasonics

Cite this

Ultrasonographic measurement of crown-rump length in high-order multifetal pregnancies. / Saade, George; Gray, G.; Belfort, M. A.; Carpenter, R. J.; Moise, K. J.

In: Ultrasound in Obstetrics and Gynecology, Vol. 11, No. 6, 1998, p. 438-444.

Research output: Contribution to journalArticle

Saade, George ; Gray, G. ; Belfort, M. A. ; Carpenter, R. J. ; Moise, K. J. / Ultrasonographic measurement of crown-rump length in high-order multifetal pregnancies. In: Ultrasound in Obstetrics and Gynecology. 1998 ; Vol. 11, No. 6. pp. 438-444.
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