TY - JOUR
T1 - Ultrasound Biomicroscopy as a Novel, Potential Modality to Evaluate Anterior Segment Ophthalmic Structures during Spaceflight
T2 - An Analysis of Current Technology
AU - Soares, Benjamin
AU - Ong, Joshua
AU - Osteicoechea, Daniela
AU - Kadipasaoglu, Cihan Mehmet
AU - Waisberg, Ethan
AU - Sarker, Prithul
AU - Zaman, Nasif
AU - Tavakkoli, Alireza
AU - Vizzeri, Gianmarco
AU - Lee, Andrew G.
N1 - Publisher Copyright:
© 2024 by the authors.
PY - 2024/3
Y1 - 2024/3
N2 - Ocular health is currently a major concern for astronauts on current and future long-duration spaceflight missions. Spaceflight-associated neuro-ocular syndrome (SANS) is a collection of ophthalmic and neurologic findings that is one potential physiologic barrier to interplanetary spaceflight. Since its initial report in 2011, our understanding of SANS has advanced considerably, with a primary focus on posterior ocular imaging including fundus photography and optical coherence tomography. However, there may be changes to the anterior segment that have not been identified. Additional concerns to ocular health in space include corneal damage and radiation-induced cataract formation. Given these concerns, precision anterior segment imaging of the eye would be a valuable addition to future long-duration spaceflights. The purpose of this paper is to review ultrasound biomicroscopy (UBM) and its potential as a noninvasive, efficient imaging modality for spaceflight. The analysis of UBM for spaceflight is not well defined in the literature, and such technology may help to provide further insights into the overall anatomical changes in the eye in microgravity.
AB - Ocular health is currently a major concern for astronauts on current and future long-duration spaceflight missions. Spaceflight-associated neuro-ocular syndrome (SANS) is a collection of ophthalmic and neurologic findings that is one potential physiologic barrier to interplanetary spaceflight. Since its initial report in 2011, our understanding of SANS has advanced considerably, with a primary focus on posterior ocular imaging including fundus photography and optical coherence tomography. However, there may be changes to the anterior segment that have not been identified. Additional concerns to ocular health in space include corneal damage and radiation-induced cataract formation. Given these concerns, precision anterior segment imaging of the eye would be a valuable addition to future long-duration spaceflights. The purpose of this paper is to review ultrasound biomicroscopy (UBM) and its potential as a noninvasive, efficient imaging modality for spaceflight. The analysis of UBM for spaceflight is not well defined in the literature, and such technology may help to provide further insights into the overall anatomical changes in the eye in microgravity.
KW - space medicine
KW - spaceflight associated neuro-ocular syndrome (SANS)
KW - ultrasound biomicroscopy (UBM)
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U2 - 10.3390/diagnostics14060639
DO - 10.3390/diagnostics14060639
M3 - Review article
C2 - 38535059
AN - SCOPUS:85188668307
SN - 2075-4418
VL - 14
JO - Diagnostics
JF - Diagnostics
IS - 6
M1 - 639
ER -