Ultrastructural characterization of a new member of the Rhabdovirus group-Klamath virus

Frederick A. Murphy, Harald N. Johnson, Alyne K. Hareison, Robert E. Shope

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Klamath virus was observed by negative contrast and thin section electron microscopy. Bullet-shaped particles in infected cell cultures had mean dimensions of 167×80 nm and were typical of members of the Rhabdovirus group. In infected mouse brain, virus particles budded from intracytoplasmic membranes in association with a prominent matrix. Although the virus is serologically unrelated to any of the known Rhabdoviruses of animals, this intracytoplasmic accumulation of virus particles and matrix with little frank cytopathology, most closely resembles in vivo rabies virus infection.

Original languageEnglish (US)
Pages (from-to)323-331
Number of pages9
JournalArchiv für die gesamte Virusforschung
Volume37
Issue number4
DOIs
StatePublished - Dec 1972

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Rhabdoviridae
Virion
Viruses
Rabies virus
Virus Diseases
Electron Microscopy
Cell Culture Techniques
Membranes
Brain

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology
  • Genetics
  • Medicine(all)

Cite this

Ultrastructural characterization of a new member of the Rhabdovirus group-Klamath virus. / Murphy, Frederick A.; Johnson, Harald N.; Hareison, Alyne K.; Shope, Robert E.

In: Archiv für die gesamte Virusforschung, Vol. 37, No. 4, 12.1972, p. 323-331.

Research output: Contribution to journalArticle

Murphy, Frederick A. ; Johnson, Harald N. ; Hareison, Alyne K. ; Shope, Robert E. / Ultrastructural characterization of a new member of the Rhabdovirus group-Klamath virus. In: Archiv für die gesamte Virusforschung. 1972 ; Vol. 37, No. 4. pp. 323-331.
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