Ultraviolet spectrophotometric assay of p-aminobenzenesulfonamides

V-M Ramanujam, Netkal M.Made Gowda, Norman M. Trieff, Marvin S. Legator

Research output: Contribution to journalArticle

Abstract

A simple ultraviolet spectrophotometric method for the assay of microgram amounts (0.1–25 μg/ml) of 16 different p-aminobenzenesulfonamides (sulfonamides) in 0.1 N sodium (Figure presented.) hydroxide has been developed. The method is simple, accurate, and highly sensitive within the limits of the experimental conditions described and can be used in pharmacies for the assay of sulfonamides in tablets and in pharmaceutical industries for quality control or environmental monitoring as well. The present method is more rapid than any analytical assay reported for these compounds thus far. The values of λmax and ϵmax for these sulfonamides have also been presented.

Original languageEnglish (US)
Pages (from-to)295-300
Number of pages6
JournalTopics in Catalysis
Volume25
Issue number3
DOIs
StatePublished - 1980

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Assays
Drug products
Tablets
Quality control
Sodium
Monitoring
Pharmaceutical Preparations
Industry
hydroxide ion

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

Cite this

Ultraviolet spectrophotometric assay of p-aminobenzenesulfonamides. / Ramanujam, V-M; Gowda, Netkal M.Made; Trieff, Norman M.; Legator, Marvin S.

In: Topics in Catalysis, Vol. 25, No. 3, 1980, p. 295-300.

Research output: Contribution to journalArticle

Ramanujam, V-M ; Gowda, Netkal M.Made ; Trieff, Norman M. ; Legator, Marvin S. / Ultraviolet spectrophotometric assay of p-aminobenzenesulfonamides. In: Topics in Catalysis. 1980 ; Vol. 25, No. 3. pp. 295-300.
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