Hipertensão pulmonar inexplicável em doentes com diálise peritoneal e hemodiálise

Translated title of the contribution: Unexplained pulmonary hypertension in peritoneal dialysis and hemodialysis patients

J. Etemadi, H. Zolfaghari, R. Firoozi, M. R. Ardalan, M. Toufan, Mohammadali Mohajel Shoja, K. Ghabili

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Objectives: To compare the prevalence of unexplained pulmonary artery hypertension (PAH) in hemodialysis (HD) and peritoneal dialysis (PD) patients and to compare laboratory parameters between patients with unexplained PAH and those with normal pulmonary artery pressure (PAP). Methods: We retrospectively reviewed the medical records of 278 chronic HD and 145 chronic PD patients. Laboratory findings including hemoglobin, calcium, phosphorus, alkaline phosphatase, albumin, parathyroid hormone level, serum iron, total iron binding capacity, ferritin, creatinine and blood urea nitrogen were documented. The results of transthoracic Doppler echocardiography were used to determine the pulmonary artery pressure (PAP). PAH was defined as a systolic pulmonary artery pressure (SPAP) ≥35 mmHg. To rule out secondary PAH, patients with cardiac disease, pulmonary disease, collagen vascular disease, volume overload at the time of echocardiography and positive human immunodeficiency virus test were excluded. Results: Data from 34 patients in group HD and 32 individuals in group PD were analyzed. The median age of the study population was 57 (45-68) years. The median SPAP value in patients with PAH was 37.5 (35-45) mmHg. According to the echocardiographic findings, PAH was found in 14 (41.1%) patients of HD group and in 6 (18.7%) patients of PD group (P = 0.04). The median serum iron and hemoglobin was significantly lower in patients with PAH compared to those in patients with normal PAP (P < 0.05). Conclusion: Unexplained PAH seems to be more frequent in patients undergoing HD than patients in PD group. Moreover, hemoglobin and serum iron levels are lower in patients with PAH compared to those in normal PAP group.

Original languagePortuguese
Pages (from-to)10-14
Number of pages5
JournalRevista Portuguesa de Pneumologia
Volume18
Issue number1
DOIs
StatePublished - Jan 1 2012
Externally publishedYes

Fingerprint

Peritoneal Dialysis
Pulmonary Hypertension
Pulmonary Artery
Renal Dialysis
Pressure
Iron
Hemoglobins
Echocardiography
Serum
Collagen Diseases
Doppler Echocardiography
Blood Urea Nitrogen
Ferritins
Parathyroid Hormone
Vascular Diseases
Phosphorus
Lung Diseases
Medical Records
Alkaline Phosphatase
Albumins

Keywords

  • Hemodialysis
  • Hypertension
  • Peritoneal dialysis
  • Pulmonary
  • Unexplained

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Etemadi, J., Zolfaghari, H., Firoozi, R., Ardalan, M. R., Toufan, M., Mohajel Shoja, M., & Ghabili, K. (2012). Hipertensão pulmonar inexplicável em doentes com diálise peritoneal e hemodiálise. Revista Portuguesa de Pneumologia, 18(1), 10-14. https://doi.org/10.1016/j.rppneu.2011.07.002

Hipertensão pulmonar inexplicável em doentes com diálise peritoneal e hemodiálise. / Etemadi, J.; Zolfaghari, H.; Firoozi, R.; Ardalan, M. R.; Toufan, M.; Mohajel Shoja, Mohammadali; Ghabili, K.

In: Revista Portuguesa de Pneumologia, Vol. 18, No. 1, 01.01.2012, p. 10-14.

Research output: Contribution to journalArticle

Etemadi, J, Zolfaghari, H, Firoozi, R, Ardalan, MR, Toufan, M, Mohajel Shoja, M & Ghabili, K 2012, 'Hipertensão pulmonar inexplicável em doentes com diálise peritoneal e hemodiálise', Revista Portuguesa de Pneumologia, vol. 18, no. 1, pp. 10-14. https://doi.org/10.1016/j.rppneu.2011.07.002
Etemadi J, Zolfaghari H, Firoozi R, Ardalan MR, Toufan M, Mohajel Shoja M et al. Hipertensão pulmonar inexplicável em doentes com diálise peritoneal e hemodiálise. Revista Portuguesa de Pneumologia. 2012 Jan 1;18(1):10-14. https://doi.org/10.1016/j.rppneu.2011.07.002
Etemadi, J. ; Zolfaghari, H. ; Firoozi, R. ; Ardalan, M. R. ; Toufan, M. ; Mohajel Shoja, Mohammadali ; Ghabili, K. / Hipertensão pulmonar inexplicável em doentes com diálise peritoneal e hemodiálise. In: Revista Portuguesa de Pneumologia. 2012 ; Vol. 18, No. 1. pp. 10-14.
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abstract = "Objectives: To compare the prevalence of unexplained pulmonary artery hypertension (PAH) in hemodialysis (HD) and peritoneal dialysis (PD) patients and to compare laboratory parameters between patients with unexplained PAH and those with normal pulmonary artery pressure (PAP). Methods: We retrospectively reviewed the medical records of 278 chronic HD and 145 chronic PD patients. Laboratory findings including hemoglobin, calcium, phosphorus, alkaline phosphatase, albumin, parathyroid hormone level, serum iron, total iron binding capacity, ferritin, creatinine and blood urea nitrogen were documented. The results of transthoracic Doppler echocardiography were used to determine the pulmonary artery pressure (PAP). PAH was defined as a systolic pulmonary artery pressure (SPAP) ≥35 mmHg. To rule out secondary PAH, patients with cardiac disease, pulmonary disease, collagen vascular disease, volume overload at the time of echocardiography and positive human immunodeficiency virus test were excluded. Results: Data from 34 patients in group HD and 32 individuals in group PD were analyzed. The median age of the study population was 57 (45-68) years. The median SPAP value in patients with PAH was 37.5 (35-45) mmHg. According to the echocardiographic findings, PAH was found in 14 (41.1{\%}) patients of HD group and in 6 (18.7{\%}) patients of PD group (P = 0.04). The median serum iron and hemoglobin was significantly lower in patients with PAH compared to those in patients with normal PAP (P < 0.05). Conclusion: Unexplained PAH seems to be more frequent in patients undergoing HD than patients in PD group. Moreover, hemoglobin and serum iron levels are lower in patients with PAH compared to those in normal PAP group.",
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KW - Unexplained

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