Unraveling drug penetration of echinocandin antifungals at the site of infection in an intra-abdominal abscess model

Keyphrases

• Infection Site 100%
• Abdominal Abscess 100%
• Drug Penetration 100%
• Abscess Model 100%
• Echinocandin Antifungal 100%
• Intra-abdominal Candidiasis 100%
• Micafungin 66%
• Echinocandins 66%
• CD101 66%
• High Mortality 33%
• Mouse Model 33%
• Therapy Control 33%
• Therapeutic Agents 33%
• Clinically Significant 33%
• Clinical Outcomes 33%
• Imaging Technology 33%
• Drug Exposure 33%
• Clinical Efficacy 33%
• Humanized 33%
• Antifungal Therapy 33%
• Source Control 33%
• Successful Treatment 33%
• Spatial Distribution 33%
• Antifungal Drugs 33%
• Drug Accumulation 33%
• Resistance Emergence 33%
• Tissue Lesion 33%
• Matrix-based 33%
• Invasive Fungal Infection 33%
• Mass Spectrometry Imaging 33%
• Quantitative Distribution 33%
• Mutant Prevention Concentration 33%
• DESI-MSI 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Infection 100%
• Abdominal Abscess 100%
• Echinocandin 100%
• Candidiasis 75%
• Micafungin 50%
• Rezafungin 50%
• Mouse Model 25%
• Tissue Injury 25%
• Antifungal Agent 25%
• Antifungal Therapy 25%
• Systemic Mycosis 25%

Immunology and Microbiology

• Abscess 100%
• Drug Penetration 100%
• Infection 100%
• Mouse Model 25%
• Drug Exposure 25%
• Desorption 25%
• Drug Accumulation 25%
• Imaging Mass Spectrometry 25%