Unraveling myasthenia gravis immunopathogenesis using animal models

Erdem Tüzün, Premkumar Christadoss

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Experimental autoimmune myasthenia gravis (EAMG), induced by immunization of animals with acetylcholine receptor, has proven to be a valuable model to understand the immunological and molecular aspects of autoimmune myasthenia gravis (MG) pathogenesis. Availability of knockout and transgenic mice has enabled the investigation of the significance of various immunological factors in MG pathogenesis. EAMG model also provides researchers a practical tool to test the efficacy of potential treatment methods for MG and for other autoimmune diseases.

Original languageEnglish
Pages (from-to)15-20
Number of pages6
JournalDrug Discovery Today: Disease Models
Volume3
Issue number1
DOIs
StatePublished - 2006

Fingerprint

Myasthenia Gravis
Autoimmune Experimental Myasthenia Gravis
Animal Models
Immunologic Factors
Cholinergic Receptors
Knockout Mice
Transgenic Mice
Autoimmune Diseases
Immunization
Research Personnel

ASJC Scopus subject areas

  • Drug Discovery
  • Molecular Medicine

Cite this

Unraveling myasthenia gravis immunopathogenesis using animal models. / Tüzün, Erdem; Christadoss, Premkumar.

In: Drug Discovery Today: Disease Models, Vol. 3, No. 1, 2006, p. 15-20.

Research output: Contribution to journalArticle

Tüzün, Erdem ; Christadoss, Premkumar. / Unraveling myasthenia gravis immunopathogenesis using animal models. In: Drug Discovery Today: Disease Models. 2006 ; Vol. 3, No. 1. pp. 15-20.
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