Ureteral axon damage following subcutaneous administration of capsaicin in adult rats

Kyungsoon Chung, Richard J. Schwen, Richarde E. Coggeshall

Research output: Contribution to journalArticle

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Abstract

Systemic administration of capsaicin to adult rats results in the death of almost 90% of the axons in the ureter. Because of the massive axon loss we presume that sensory and possibly some sympathetic axons are killed. By contrast sensory axons in the dorsal root do not seem to be affected. We speculate that the axons in the ureter die because they are not protected by sleeves of perineurium. This hypothesis will be tested in subsequent work.

Original languageEnglish (US)
Pages (from-to)221-226
Number of pages6
JournalNeuroscience Letters
Volume53
Issue number2
DOIs
StatePublished - Jan 21 1985

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Keywords

  • capsaicin
  • rat
  • unmyelinated axons
  • ureter

ASJC Scopus subject areas

  • Neuroscience(all)

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