Abstract
Hepatopulmonary syndrome (HPS) is defined by the presence of the triad of liver disease, arterial hypoxemia, and intrapulmonary vascular dilatation. The clinical implication of this disorder is impairment of gas exchange. Numerous reports in the literature show that this condition is reversible with orthotopic liver transplantation (OLT). However, patients with HPS often present with Pao 2 levels that are quite low. OLT with a preoperative Pao 2 less than 50 mm Hg is associated with unacceptably high mortality and morbidity. We report a case of severe HPS in which a transjugular intrahepatic portosystemic shunt was successfully used to improve oxygenation, thus allowing a successful elective OLT.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 147-149 |
| Number of pages | 3 |
| Journal | Liver Transplantation |
| Volume | 7 |
| Issue number | 2 |
| DOIs | |
| State | Published - 2001 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Surgery
- Transplantation
Cite this
Use of transjugular intrahepatic portosystemic shunt as a bridge to liver transplantation in a patient with severe hepatopulmonary syndrome. / Lasch, Hugh M.; Fried, Michael W.; Zacks, Steven L.; Odell, Pat; Johnson, Mark W.; Gerber, David A.; Sandhu, Fatejeet S.; Fair, Jeffrey; Shrestha, Roshan.
In: Liver Transplantation, Vol. 7, No. 2, 2001, p. 147-149.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Use of transjugular intrahepatic portosystemic shunt as a bridge to liver transplantation in a patient with severe hepatopulmonary syndrome
AU - Lasch, Hugh M.
AU - Fried, Michael W.
AU - Zacks, Steven L.
AU - Odell, Pat
AU - Johnson, Mark W.
AU - Gerber, David A.
AU - Sandhu, Fatejeet S.
AU - Fair, Jeffrey
AU - Shrestha, Roshan
PY - 2001
Y1 - 2001
N2 - Hepatopulmonary syndrome (HPS) is defined by the presence of the triad of liver disease, arterial hypoxemia, and intrapulmonary vascular dilatation. The clinical implication of this disorder is impairment of gas exchange. Numerous reports in the literature show that this condition is reversible with orthotopic liver transplantation (OLT). However, patients with HPS often present with Pao 2 levels that are quite low. OLT with a preoperative Pao 2 less than 50 mm Hg is associated with unacceptably high mortality and morbidity. We report a case of severe HPS in which a transjugular intrahepatic portosystemic shunt was successfully used to improve oxygenation, thus allowing a successful elective OLT.
AB - Hepatopulmonary syndrome (HPS) is defined by the presence of the triad of liver disease, arterial hypoxemia, and intrapulmonary vascular dilatation. The clinical implication of this disorder is impairment of gas exchange. Numerous reports in the literature show that this condition is reversible with orthotopic liver transplantation (OLT). However, patients with HPS often present with Pao 2 levels that are quite low. OLT with a preoperative Pao 2 less than 50 mm Hg is associated with unacceptably high mortality and morbidity. We report a case of severe HPS in which a transjugular intrahepatic portosystemic shunt was successfully used to improve oxygenation, thus allowing a successful elective OLT.
UR - http://www.scopus.com/inward/record.url?scp=0035107709&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035107709&partnerID=8YFLogxK
U2 - 10.1053/jlts.2001.21287
DO - 10.1053/jlts.2001.21287
M3 - Article
VL - 7
SP - 147
EP - 149
JO - Liver Transplantation
JF - Liver Transplantation
SN - 1527-6465
IS - 2
ER -