Abstract
A gold nanoparticles functionalization experiment was conducted in a biotechnology summer course at UFOP as a model for the introduction of the laboratory practice in nanotechnology for postgraduate courses in the areas of chemistry and biotechnology. The gold nanorods were synthesized by the seed method and then, functionalized with anti-IL-6 antibodies using the reagents EDAC/NHS and polyethyleneimine (PEI). This nanocompound was tested against the binding with the specifc antigen (IL-6) and changes in the longitudinal plasmon absorption spectrum showed the coupling effciency, which was also verifed by the decrease in zeta potential. The experiment was satisfactory, with a positive feedback from participants, and could be implemented in nanotechnology practical classes from postgraduate courses, as a way for improve education in the emergent area of nanobiotechnology.
Translated title of the contribution | Use of gold nanorods for the development of practical classes in nanotechnology |
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Original language | Portuguese |
Pages (from-to) | 594-601 |
Number of pages | 8 |
Journal | Quimica Nova |
Volume | 40 |
Issue number | 5 |
DOIs | |
State | Published - Jun 2017 |
Externally published | Yes |
Keywords
- Gold nanorods
- Nanotechnology experiment
- Surface plasmon resonance
ASJC Scopus subject areas
- General Chemistry