Uso de nanobastÕes de ouro para o desenvolvimento de aulas prÁticas de nanotecnologia

Translated title of the contribution: Use of gold nanorods for the development of practical classes in nanotechnology

Cyntia Silva Ferreira, Luiz Orlando Ladeira, Cristiano Fantini Leite, Flávio Guimarães Da Fonseca, Erica Milena De Castro Ribeiro, Alice Freitas Versiani, Jorge Fernando De Souza Silva, Cíntia Lopes De Brito Magalhães, Breno De Mello Silva

Research output: Contribution to journalArticlepeer-review

Abstract

A gold nanoparticles functionalization experiment was conducted in a biotechnology summer course at UFOP as a model for the introduction of the laboratory practice in nanotechnology for postgraduate courses in the areas of chemistry and biotechnology. The gold nanorods were synthesized by the seed method and then, functionalized with anti-IL-6 antibodies using the reagents EDAC/NHS and polyethyleneimine (PEI). This nanocompound was tested against the binding with the specifc antigen (IL-6) and changes in the longitudinal plasmon absorption spectrum showed the coupling effciency, which was also verifed by the decrease in zeta potential. The experiment was satisfactory, with a positive feedback from participants, and could be implemented in nanotechnology practical classes from postgraduate courses, as a way for improve education in the emergent area of nanobiotechnology.

Translated title of the contributionUse of gold nanorods for the development of practical classes in nanotechnology
Original languagePortuguese
Pages (from-to)594-601
Number of pages8
JournalQuimica Nova
Volume40
Issue number5
DOIs
StatePublished - Jun 2017
Externally publishedYes

Keywords

  • Gold nanorods
  • Nanotechnology experiment
  • Surface plasmon resonance

ASJC Scopus subject areas

  • General Chemistry

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