Uterine electromyography and light-induced fluorescence in the management of term and preterm labor

R. E. Garfield, H. Maul, W. Maner, C. Fittkow, Gayle Olson, L. Shi, George Saade

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Objective: Understanding the physiology of the uterus and cervix during term and preterm parturition is crucial for developing methods to control their function and is essential to solving clinical problems related to labor. To date, only crude, inaccurate, and subjective methods are used to assess changes in uterine and cervical function in pregnancy. Methods: In the past several years, we have developed noninvasive methods to quantitatively evaluate the uterus and cervix based on recording of uterine electrical signals from the abdominal surface (uterine electromyography) and measurement of light-induced fluorescence (LIF) of cervical collagen (Collascope), respectively. Both methods are rapid and allow immediate assessment of uterine contractility and cervical ripening. Results: Studies in animals and humans indicated that uterine and cervical performance can be monitored successfully during pregnancy using those approaches and that these techniques can be used during labor to better define management in a variety of conditions associated with labor. Conclusions: The potential benefits of the proposed instrumentation and methods include reducing the rate of preterm delivery, improving maternal and perinatal outcome, monitoring treatment, decreasing cesarean rate and providing research methods to understand uterine and cervical function.

Original languageEnglish (US)
Pages (from-to)265-275
Number of pages11
JournalJournal of the Society for Gynecologic Investigation
Volume9
Issue number5
DOIs
StatePublished - Sep 10 2002

Fingerprint

Premature Obstetric Labor
Electromyography
Fluorescence
Light
Cervix Uteri
Cervical Ripening
Pregnancy
Collagen
Mothers
Parturition
Research

Keywords

  • Cervix
  • Collascope
  • Electromyography
  • Myometrium
  • Preterm labor

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Uterine electromyography and light-induced fluorescence in the management of term and preterm labor. / Garfield, R. E.; Maul, H.; Maner, W.; Fittkow, C.; Olson, Gayle; Shi, L.; Saade, George.

In: Journal of the Society for Gynecologic Investigation, Vol. 9, No. 5, 10.09.2002, p. 265-275.

Research output: Contribution to journalArticle

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