Vaccines for Venezuelan equine encephalitis

Research output: Contribution to journalArticle

63 Scopus citations

Abstract

Arboviruses are capable of causing encephalitis in animals and human population when transmitted by the vector or potentially via infectious aerosol. Recent re-emergence of Venezuelan equine encephalitis virus (VEEV) in South America emphasizes the importance of this pathogen to public health and veterinary medicine. Despite its importance no antivirals or vaccines against VEEV are currently available in the USA. Here we review some of the older and newer approaches aimed at generating a safe and immunogenic vaccine as well as most recent data about the mechanistic of protection in animal models of infection.

Original languageEnglish (US)
Pages (from-to)D80-D85
JournalVaccine
Volume27
Issue numberSUPPL. 4
DOIs
StatePublished - Nov 5 2009

Keywords

  • Encephalitis
  • Togaviridae
  • Vaccines

ASJC Scopus subject areas

  • Molecular Medicine
  • Immunology and Microbiology(all)
  • veterinary(all)
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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