TY - JOUR
T1 - Variation in the susceptibility of strains of Staphylococcus aureus to oxacillin, cephalothin, and gentamicin
AU - Mayhall, C. G.
AU - Medoff, G.
AU - Marr, J. J.
PY - 1976
Y1 - 1976
N2 - Three cases of staphylococcal bacteremia caused by organisms that were inhibited by low concentrations of oxacillin, but were resistant to the killing effects of oxacillin, stimulated the authors to screen 60 clinical isolates of Staphylococcus aureus for their susceptibility to oxacillin, cephalothin, and gentamicin. All 60 strains were inhibited by low concentrations of the antibiotics. The antibiotics were bactericidal against 27 of the 60 strains and only bacteriostatic against the other 33 after 24 h of incubation. However, after 48 h of incubation, the antibiotics were also bactericidal against the latter group.
AB - Three cases of staphylococcal bacteremia caused by organisms that were inhibited by low concentrations of oxacillin, but were resistant to the killing effects of oxacillin, stimulated the authors to screen 60 clinical isolates of Staphylococcus aureus for their susceptibility to oxacillin, cephalothin, and gentamicin. All 60 strains were inhibited by low concentrations of the antibiotics. The antibiotics were bactericidal against 27 of the 60 strains and only bacteriostatic against the other 33 after 24 h of incubation. However, after 48 h of incubation, the antibiotics were also bactericidal against the latter group.
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U2 - 10.1128/AAC.10.4.707
DO - 10.1128/AAC.10.4.707
M3 - Article
C2 - 984804
AN - SCOPUS:0017190295
SN - 0066-4804
VL - 10
SP - 707
EP - 712
JO - Antimicrobial agents and chemotherapy
JF - Antimicrobial agents and chemotherapy
IS - 4
ER -