Vector competence of aedes aegypti and aedes vittatus (Diptera: Culicidae) from Senegal and Cape Verde archipelago for West African lineages of chikungunya virus

Cheikh T. Diagne, Oumar Faye, Mathilde Guerbois, Rachel Knight, Diawo Diallo, Ousmane Faye, Yamar Ba, Ibrahima Dia, Scott Weaver, Amadou A. Sall, Mawlouth Diallo

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

To assess the risk of emergence of chikungunya virus (CHIKV) in West Africa, vector competence of wildtype, urban, and non-urban Aedes aegypti and Ae. vittatus from Senegal and Cape Verde for CHIKV was investigated. Mosquitoes were fed orally with CHIKV isolates from mosquitoes (ArD30237), bats (CS13-288), and humans (HD180738). After 5, 10, and 15 days of incubation following an infectious blood meal, presence of CHIKV RNA was determined in bodies, legs/wings, and saliva using real-time reverse transcription-polymerase chain reaction. Aedes vittatus showed high susceptibility (50-100%) and early dissemination and transmission of all CHIKV strains tested. Aedes aegypti exhibited infection rates ranging from 0% to 50%. Aedes aegypti from Cape Verde and Kedougou, but not those from Dakar, showed the potential to transmit CHIKV in saliva. Analysis of biology and competence showed relatively high infective survival rates for Ae. vittatus and Ae. aegypti from Cape Verde, suggesting their efficient vector capacity in West Africa. Copyright

Original languageEnglish (US)
Pages (from-to)635-641
Number of pages7
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume91
Issue number3
DOIs
StatePublished - Sep 1 2014

    Fingerprint

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases
  • Virology
  • Medicine(all)

Cite this