Vesicle movements and microtubule-based motors.

Michael Sheetz, R. Vale, B. Schnapp, T. Schroer, T. Reese

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

The movements of many cytoplasmic vesicles follow the paths of microtubules, some moving in one direction and others moving in the opposite direction on the same microtubule. Recently we have isolated one cytoplasmic motor, kinesin, and defined another, the axoplasmic retrograde factor, both of which are capable of powering anionic latex beads in both directions along polar microtubule arrays. Evidence summarized here supports but does not prove the hypothesis that kinesin and the retrograde motors are indeed responsible for powering vesicle movements.

Original languageEnglish (US)
Pages (from-to)181-188
Number of pages8
JournalJournal of cell science. Supplement
Volume5
StatePublished - Jan 1 1986
Externally publishedYes

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Microtubules
Kinesin
Cytoplasmic Vesicles
Microspheres
Direction compound

Cite this

Sheetz, M., Vale, R., Schnapp, B., Schroer, T., & Reese, T. (1986). Vesicle movements and microtubule-based motors. Journal of cell science. Supplement, 5, 181-188.

Vesicle movements and microtubule-based motors. / Sheetz, Michael; Vale, R.; Schnapp, B.; Schroer, T.; Reese, T.

In: Journal of cell science. Supplement, Vol. 5, 01.01.1986, p. 181-188.

Research output: Contribution to journalArticle

Sheetz, M, Vale, R, Schnapp, B, Schroer, T & Reese, T 1986, 'Vesicle movements and microtubule-based motors.', Journal of cell science. Supplement, vol. 5, pp. 181-188.
Sheetz M, Vale R, Schnapp B, Schroer T, Reese T. Vesicle movements and microtubule-based motors. Journal of cell science. Supplement. 1986 Jan 1;5:181-188.
Sheetz, Michael ; Vale, R. ; Schnapp, B. ; Schroer, T. ; Reese, T. / Vesicle movements and microtubule-based motors. In: Journal of cell science. Supplement. 1986 ; Vol. 5. pp. 181-188.
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