Vesicular stomatitis virus (Indiana serotype): Transovarial transmission by phlebotomine sandflies

Robert B. Tesh, Byron N. Chaniotis, Karl M. Johnson

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

Transovarial transmission of vesicular stomatitis virus (Indiana serotype) by experimentally infected Lutzomyia trapidoi and Lutzomyia ylephiletrix to their progeny was demonstrated. Virus was recovered from all developmental stages; mean virus titers from egg to first generation adult showed a four-log increase, indicating that virus multiplication occurred during development of the sandflies. Virus titers in first generation adult females were comparable to those found in their parents. These infected female sandflies transmitted vesicular stomatitus virus Indiana by bite to susceptible animals and transmitted the virus transovarially to their offspring (second generation). Results demonstrate a possible mechanism for transmission and maintenance of this virus in nature without a vertebrate (heat) host reservoir.

Original languageEnglish (US)
Pages (from-to)1477-1479
Number of pages3
JournalScience
Volume175
Issue number4029
StatePublished - 1972
Externally publishedYes

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Vesicular stomatitis Indiana virus
Psychodidae
Viruses
Viral Load
Bites and Stings
Ovum
Vertebrates
Hot Temperature
Maintenance
Serogroup

ASJC Scopus subject areas

  • General

Cite this

Tesh, R. B., Chaniotis, B. N., & Johnson, K. M. (1972). Vesicular stomatitis virus (Indiana serotype): Transovarial transmission by phlebotomine sandflies. Science, 175(4029), 1477-1479.

Vesicular stomatitis virus (Indiana serotype) : Transovarial transmission by phlebotomine sandflies. / Tesh, Robert B.; Chaniotis, Byron N.; Johnson, Karl M.

In: Science, Vol. 175, No. 4029, 1972, p. 1477-1479.

Research output: Contribution to journalArticle

Tesh, RB, Chaniotis, BN & Johnson, KM 1972, 'Vesicular stomatitis virus (Indiana serotype): Transovarial transmission by phlebotomine sandflies', Science, vol. 175, no. 4029, pp. 1477-1479.
Tesh, Robert B. ; Chaniotis, Byron N. ; Johnson, Karl M. / Vesicular stomatitis virus (Indiana serotype) : Transovarial transmission by phlebotomine sandflies. In: Science. 1972 ; Vol. 175, No. 4029. pp. 1477-1479.
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