Vesicular stomatitis virus, New Jersey serotype

Replication in and transmission by Lutzomyia shannon (Diptera: psychodidae)

J. A. Comer, R. B. Tesh, G. B. Modi, J. L. Corn, V. F. Nettles

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

Laboratory-reared female sand flies (Lutzomyia shannoni) were experimentally infected, orally and by intrathoracic inoculation, with the New Jersey serotype of vesicular stomatitis (VSNJ) virus. Virus replication occurred in the insects following infection by both routes. Virus titers > 104 plaque forming units of VSNJ virus were present in heads of orally infected sand flies 12 days after virus ingestion, confirming that a persistent disseminated infection had occurred. Both orally and parenterally infected Lu. shannoni transmitted VSNJ virus by bite to susceptible rodents and by transovarial transmission to a small percentage of their F1 progeny. The significance of these findings in the epizootiology of VSNJ virus on Ossabaw Island, Georgia, an enzootic focus of this virus, is discussed.

Original languageEnglish (US)
Pages (from-to)483-490
Number of pages8
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume42
Issue number5
StatePublished - 1990
Externally publishedYes

Fingerprint

Vesicular stomatitis New Jersey virus
Psychodidae
Diptera
Viruses
Vesicular Stomatitis
Bites and Stings
Virus Replication
Infection
Viral Load
Islands
Insects
Serogroup
Rodentia
Eating
Head

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Vesicular stomatitis virus, New Jersey serotype : Replication in and transmission by Lutzomyia shannon (Diptera: psychodidae). / Comer, J. A.; Tesh, R. B.; Modi, G. B.; Corn, J. L.; Nettles, V. F.

In: American Journal of Tropical Medicine and Hygiene, Vol. 42, No. 5, 1990, p. 483-490.

Research output: Contribution to journalArticle

Comer, J. A. ; Tesh, R. B. ; Modi, G. B. ; Corn, J. L. ; Nettles, V. F. / Vesicular stomatitis virus, New Jersey serotype : Replication in and transmission by Lutzomyia shannon (Diptera: psychodidae). In: American Journal of Tropical Medicine and Hygiene. 1990 ; Vol. 42, No. 5. pp. 483-490.
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