Viral DNA sequences in human cytomegalovirus transformed hamster cell line at low passage levels.

Istvan Boldogh, B. Brichacek, E. Gönczöl, I. Hirsch, L. Váczi

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The characteristics of a human cytomegalovirus (HCMV) transformed syrian hamster cell line (87-TRH-5) were examined. The cytomegalovirus DNA (HCMV-DNA) labelled in vitro by nick translation was used as a probe to detect viral DNA sequences in the 87-TRH-5 line. Cytomegalovirus specified DNA sequences were detected in cells examined up to passage 58, but were undetectable at higher passage levels. Six clones were derived from the 28th passage of 87-TRH-5 cells and examined for HCMV-DNA sequences. Various amounts of HCMV-DNA were found. A tumour induced by passage 28 cells contained no detectable HCMV-DNA sequences.

Original languageEnglish (US)
Pages (from-to)147-154
Number of pages8
JournalActa Microbiologica Hungarica
Volume32
Issue number2
StatePublished - 1985
Externally publishedYes

Fingerprint

Transformed Cell Line
Viral DNA
Cytomegalovirus
Cricetinae
DNA
Mesocricetus
Clone Cells
Cell Line

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

Cite this

Viral DNA sequences in human cytomegalovirus transformed hamster cell line at low passage levels. / Boldogh, Istvan; Brichacek, B.; Gönczöl, E.; Hirsch, I.; Váczi, L.

In: Acta Microbiologica Hungarica, Vol. 32, No. 2, 1985, p. 147-154.

Research output: Contribution to journalArticle

Boldogh, I, Brichacek, B, Gönczöl, E, Hirsch, I & Váczi, L 1985, 'Viral DNA sequences in human cytomegalovirus transformed hamster cell line at low passage levels.', Acta Microbiologica Hungarica, vol. 32, no. 2, pp. 147-154.
Boldogh, Istvan ; Brichacek, B. ; Gönczöl, E. ; Hirsch, I. ; Váczi, L. / Viral DNA sequences in human cytomegalovirus transformed hamster cell line at low passage levels. In: Acta Microbiologica Hungarica. 1985 ; Vol. 32, No. 2. pp. 147-154.
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