Viral metagenomics, protein structure, and reverse genetics: Key strategies for investigating coronaviruses

Bryan Johnson, Rachel L. Graham, Vineet Menachery

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Viral metagenomics, modeling of protein structure, and manipulation of viral genetics are key approaches that have laid the foundations of our understanding of coronavirus biology. In this review, we discuss the major advances each method has provided and discuss how future studies should leverage these strategies synergistically to answer novel questions.

Original languageEnglish (US)
JournalVirology
DOIs
StateAccepted/In press - Jan 1 2017

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ASJC Scopus subject areas

  • Virology

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