Viral metagenomics, protein structure, and reverse genetics: Key strategies for investigating coronaviruses

Bryan A. Johnson, Rachel L. Graham, Vineet D. Menachery

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Viral metagenomics, modeling of protein structure, and manipulation of viral genetics are key approaches that have laid the foundations of our understanding of coronavirus biology. In this review, we discuss the major advances each method has provided and discuss how future studies should leverage these strategies synergistically to answer novel questions.

Original languageEnglish (US)
Pages (from-to)30-37
Number of pages8
JournalVirology
Volume517
DOIs
StatePublished - Apr 2018

ASJC Scopus subject areas

  • Virology

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