Viral metagenomics, protein structure, and reverse genetics: Key strategies for investigating coronaviruses

Bryan A. Johnson; Rachel L. Graham; Vineet D. Menachery

doi:10.1016/j.virol.2017.12.009

Viral metagenomics, protein structure, and reverse genetics: Key strategies for investigating coronaviruses

Bryan A. Johnson
, Rachel L. Graham
, Vineet D. Menachery

Microbiology And Immunology

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Viral metagenomics, modeling of protein structure, and manipulation of viral genetics are key approaches that have laid the foundations of our understanding of coronavirus biology. In this review, we discuss the major advances each method has provided and discuss how future studies should leverage these strategies synergistically to answer novel questions.

Original language	English (US)
Pages (from-to)	30-37
Number of pages	8
Journal	Virology
Volume	517
DOIs	https://doi.org/10.1016/j.virol.2017.12.009
State	Published - Apr 2018

ASJC Scopus subject areas

Virology

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10.1016/j.virol.2017.12.009

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title = "Viral metagenomics, protein structure, and reverse genetics: Key strategies for investigating coronaviruses",

abstract = "Viral metagenomics, modeling of protein structure, and manipulation of viral genetics are key approaches that have laid the foundations of our understanding of coronavirus biology. In this review, we discuss the major advances each method has provided and discuss how future studies should leverage these strategies synergistically to answer novel questions.",

author = "Johnson, \{Bryan A.\} and Graham, \{Rachel L.\} and Menachery, \{Vineet D.\}",

note = "Publisher Copyright: {\textcopyright} 2017 Elsevier Inc.",

year = "2018",

month = apr,

doi = "10.1016/j.virol.2017.12.009",

language = "English (US)",

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journal = "Virology",

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T2 - Key strategies for investigating coronaviruses

AU - Johnson, Bryan A.

AU - Graham, Rachel L.

AU - Menachery, Vineet D.

PY - 2018/4

Y1 - 2018/4

N2 - Viral metagenomics, modeling of protein structure, and manipulation of viral genetics are key approaches that have laid the foundations of our understanding of coronavirus biology. In this review, we discuss the major advances each method has provided and discuss how future studies should leverage these strategies synergistically to answer novel questions.

AB - Viral metagenomics, modeling of protein structure, and manipulation of viral genetics are key approaches that have laid the foundations of our understanding of coronavirus biology. In this review, we discuss the major advances each method has provided and discuss how future studies should leverage these strategies synergistically to answer novel questions.

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UR - https://www.scopus.com/pages/publications/85039552156#tab=citedBy

U2 - 10.1016/j.virol.2017.12.009

DO - 10.1016/j.virol.2017.12.009

M3 - Article

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AN - SCOPUS:85039552156

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VL - 517

SP - 30

EP - 37

JO - Virology

JF - Virology

ER -

Viral metagenomics, protein structure, and reverse genetics: Key strategies for investigating coronaviruses

Abstract

ASJC Scopus subject areas

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