Visceral target organs in systemic St. Louis encephalitis virus infection of hamsters

Alyne K. Harrison, Frederick A. Murphy, Jared J. Gardner

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Ultrastructural aspects of St. Louis encephalitis virus infection of the major extraneutral organs and tissues of suckling hamsters were examined. In the pancreas, both the exocrine and endocrine portions were equally affected by the virus. A feature apparently unique to flaviviruses was the accumulation of virus particles in all types of secretory granules in this organ. Virus particles were seen within myocardial fibers and within the smooth muscle cells and endothelial cells of small blood vessels of the heart. In the intestines, the lamina propria was the most severely infected, with virus particles accumulated in all cell types.

Original languageEnglish (US)
Pages (from-to)292-304
Number of pages13
JournalExperimental and Molecular Pathology
Volume37
Issue number3
DOIs
StatePublished - 1982

Fingerprint

St. Louis Encephalitis Viruses
Virus Diseases
Viruses
Cricetinae
Virion
Flavivirus
Exocrine Pancreas
Secretory Vesicles
Islets of Langerhans
Smooth Muscle Myocytes
Intestines
Blood Vessels
Mucous Membrane
Endothelial Cells
Endothelial cells
Blood vessels
Muscle
Cells
Infectious Encephalitis
Tissue

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Molecular Biology
  • Pathology and Forensic Medicine

Cite this

Visceral target organs in systemic St. Louis encephalitis virus infection of hamsters. / Harrison, Alyne K.; Murphy, Frederick A.; Gardner, Jared J.

In: Experimental and Molecular Pathology, Vol. 37, No. 3, 1982, p. 292-304.

Research output: Contribution to journalArticle

Harrison, Alyne K. ; Murphy, Frederick A. ; Gardner, Jared J. / Visceral target organs in systemic St. Louis encephalitis virus infection of hamsters. In: Experimental and Molecular Pathology. 1982 ; Vol. 37, No. 3. pp. 292-304.
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