Visceral target organs in systemic St. Louis encephalitis virus infection of hamsters

Alyne K. Harrison, Frederick A. Murphy, Jared J. Gardner

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Ultrastructural aspects of St. Louis encephalitis virus infection of the major extraneutral organs and tissues of suckling hamsters were examined. In the pancreas, both the exocrine and endocrine portions were equally affected by the virus. A feature apparently unique to flaviviruses was the accumulation of virus particles in all types of secretory granules in this organ. Virus particles were seen within myocardial fibers and within the smooth muscle cells and endothelial cells of small blood vessels of the heart. In the intestines, the lamina propria was the most severely infected, with virus particles accumulated in all cell types.

Original languageEnglish (US)
Pages (from-to)292-304
Number of pages13
JournalExperimental and Molecular Pathology
Volume37
Issue number3
DOIs
StatePublished - Dec 1982

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Molecular Biology
  • Clinical Biochemistry

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