Weathering the storm: A case of thyroid storm refractory to conventional treatment benefiting from therapeutic plasma exchange

Aaron J. Wyble, Steven C. Moore, Sean Yates

Research output: Contribution to journalArticle


Thyroid storm is a severe manifestation of thyrotoxicosis characterized by systemic organ dysfunction secondary to a hypermetabolic state. Although antithyroid drugs, steroids, beta-blockers, antipyretics, and cholestyramine are the standard of care, some patients inadequately respond to these conventional therapies. Therapeutic plasma exchange has been previously utilized as a treatment modality in patients with a poor response to routine therapies or with contraindications to them. Herein, we report our experience with the management of a case of thyroid storm refractory to conventional treatment but responsive to therapeutic plasma exchange.

Original languageEnglish (US)
Pages (from-to)678-681
Number of pages4
JournalJournal of Clinical Apheresis
Issue number6
StatePublished - Dec 1 2018



  • Graves' disease
  • therapeutic plasma exchange
  • thyrotoxicosis

ASJC Scopus subject areas

  • Hematology

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