What, How, and How Much Should Patients with Burns be Fed?

Felicia N. Williams, Ludwik K. Branski, Marc G. Jeschke, David N. Herndon

Research output: Contribution to journalReview articlepeer-review

56 Scopus citations


The hypermetabolic response to severe burn injury is characterized by hyperdynamic circulation and profound metabolic, physiologic, catabolic, and immune system derangements. Failure to satisfy overwhelming energy and protein requirements after, and during, severe burn injury results in multiorgan dysfunction, increased susceptibility to infection, and death. Attenuation of the hypermetabolic response by various pharmacologic modalities is emerging as an essential component of the management of patients with severe burn injury. This review focuses on the more recent advances in therapeutic strategies to attenuate the hypermetabolic response and its postburn-associated insulin resistance.

Original languageEnglish (US)
Pages (from-to)609-629
Number of pages21
JournalSurgical Clinics of North America
Issue number3
StatePublished - Jun 2011


  • Burn injury
  • Hypermetabolic response
  • Nutrition
  • Trauma

ASJC Scopus subject areas

  • Surgery


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