Whipple's disease can mimic chronic AIDS enteropathy

G. M. Maliha, K. S. Hepps, D. M. Maia, K. R. Gentry, A. E. Fraire, R. W. Goodgame

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Previous case reports have demonstrated that the intestinal pathology of Mycobacterium avium-intracellulare (MAI) infection in the acquired immune deficiency syndrome (AIDS) has a light microscopic appearance similar to Whipple's disease. This case report describes a 52-yr-old male patient with a clinical picture suggestive of AIDS, including diarrhea, weight loss, oral thrush, and intestinal cryptosporidiosis. The intestinal biopsy showed light microscopic features compatible with either MAI or Whipple's disease, but electron microscopy confirmed the presence of the Whipple bacillus. Markers of human immunodeficiency virus (HIV) infection were absent. Although immune abnormalities have been reported in Whipple's disease, this is the first report of opportunistic infections complicating this condition. A useful clinical pearl emerges from this and other cases: AIDS can mimic Whipple's disease; Whipple's disease can mimic AIDS.

Original languageEnglish (US)
Pages (from-to)79-81
Number of pages3
JournalAmerican Journal of Gastroenterology
Volume86
Issue number1
StatePublished - 1991
Externally publishedYes

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Whipple Disease
Acquired Immunodeficiency Syndrome
Mycobacterium avium-intracellulare Infection
Oral Candidiasis
Cryptosporidiosis
Light
Mycobacterium avium Complex
Opportunistic Infections
Virus Diseases
Bacillus
Weight Loss
Diarrhea
Electron Microscopy
HIV
Pathology
Biopsy

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Maliha, G. M., Hepps, K. S., Maia, D. M., Gentry, K. R., Fraire, A. E., & Goodgame, R. W. (1991). Whipple's disease can mimic chronic AIDS enteropathy. American Journal of Gastroenterology, 86(1), 79-81.

Whipple's disease can mimic chronic AIDS enteropathy. / Maliha, G. M.; Hepps, K. S.; Maia, D. M.; Gentry, K. R.; Fraire, A. E.; Goodgame, R. W.

In: American Journal of Gastroenterology, Vol. 86, No. 1, 1991, p. 79-81.

Research output: Contribution to journalArticle

Maliha, GM, Hepps, KS, Maia, DM, Gentry, KR, Fraire, AE & Goodgame, RW 1991, 'Whipple's disease can mimic chronic AIDS enteropathy', American Journal of Gastroenterology, vol. 86, no. 1, pp. 79-81.
Maliha GM, Hepps KS, Maia DM, Gentry KR, Fraire AE, Goodgame RW. Whipple's disease can mimic chronic AIDS enteropathy. American Journal of Gastroenterology. 1991;86(1):79-81.
Maliha, G. M. ; Hepps, K. S. ; Maia, D. M. ; Gentry, K. R. ; Fraire, A. E. ; Goodgame, R. W. / Whipple's disease can mimic chronic AIDS enteropathy. In: American Journal of Gastroenterology. 1991 ; Vol. 86, No. 1. pp. 79-81.
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