TY - JOUR
T1 - Wound coverage technologies in burn care
T2 - Novel techniques
AU - Jeschke, Marc G.
AU - Finnerty, Celeste C.
AU - Shahrokhi, Shahriar
AU - Branski, Ludwik K.
AU - Dibildox, Manuel
PY - 2013
Y1 - 2013
N2 - Improvements in burn wound care have vastly decreased morbidity and mortality in severely burned patients. Development of new therapeutic approaches to increase wound repair has the potential to reduce infection, graft rejection, and hypertrophic scarring. The incorporation of tissue-engineering techniques, along with the use of exogenous proteins, genes, or stem cells to enhance wound healing, heralds new treatment regimens based on the modification of already existing biological activity. Refinements to surgical techniques have enabled the creation of protocols for full facial transplantation. With new technologies and advances such as these, care of the severely burned will undergo massive changes over the next decade. This review centers on new developments that have recently shown great promise in the investigational arena.
AB - Improvements in burn wound care have vastly decreased morbidity and mortality in severely burned patients. Development of new therapeutic approaches to increase wound repair has the potential to reduce infection, graft rejection, and hypertrophic scarring. The incorporation of tissue-engineering techniques, along with the use of exogenous proteins, genes, or stem cells to enhance wound healing, heralds new treatment regimens based on the modification of already existing biological activity. Refinements to surgical techniques have enabled the creation of protocols for full facial transplantation. With new technologies and advances such as these, care of the severely burned will undergo massive changes over the next decade. This review centers on new developments that have recently shown great promise in the investigational arena.
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U2 - 10.1097/BCR.0b013e31829b0075
DO - 10.1097/BCR.0b013e31829b0075
M3 - Article
C2 - 23877140
AN - SCOPUS:84892822870
SN - 1559-047X
VL - 34
SP - 612
EP - 620
JO - Journal of Burn Care and Research
JF - Journal of Burn Care and Research
IS - 6
ER -