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X-ray structure of PTP1B in complex with a new PTP1B inhibitor
M. V.V.V.Sekhar Reddy
, Chakshumathi Ghadiyaram
, Sunil Kumar Panigrahi
, Narasimha Rao Krishnamurthy
, Subramanya Hosahalli
, Arun P. Chandrasekharappa
, Dipankar Manna
, Sangamesh E. Badiger
, Pramod K. Dubey
, Lakshmi Narasu Mangamoori
Research output
:
Contribution to journal
›
Article
›
peer-review
16
Scopus citations
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Keyphrases
X-ray Structure
100%
Protein Structure
100%
Protein Tyrosine Phosphatase 1B (PTP1B)
100%
Protein Tyrosine Phosphatase 1B Inhibitor
100%
Obesity
12%
Knock-in Mouse Model
12%
Antisense
12%
Effective Strategies
12%
Allosteric Site
12%
Molecular Interactions
12%
Catalytic Site
12%
Binding Residues
12%
Replacement Method
12%
Asymmetric Unit
12%
Type 2 Diabetes Prevention
12%
Leptin Signaling
12%
Insulin Signaling Pathway
12%
Molecular Replacement
12%
Cell Dimension
12%
Biochemistry, Genetics and Molecular Biology
X Ray
100%
Protein Tyrosine Phosphatase
100%
Crystal Structure
22%
Knockout Mouse
11%
Antisense
11%
Enzyme
11%
Active Site
11%
Molecular Interaction
11%
Allosteric Site
11%
Leptin
11%
Pharmacology, Toxicology and Pharmaceutical Science
Protein Tyrosine Phosphatase 1B Inhibitor
100%
Protein Tyrosine Phosphatase 1B
100%
Knockout Mouse
12%
Leptin
12%
Cytoplasmic Receptor
12%
Maturity Onset Diabetes of the Young
12%