Abstract
Zika virus was discovered in East Africa in 1947 and remained an obscure mosquito-borne virus until its first documented epidemic in 2007. Its introduction in the Western Hemisphere in 2015 has been accompanied by the emergence of rare disease manifestations, notably congenital Zika syndrome and Guillain-Barré syndrome. The widespread establishment of authochtonous transmission cycles throughout the tropics and subtropical areas, has put a third of the global population at risk of infection and a race to understand the mechanisms of pathogenesis and development of effective coutntermeasures in controlling its spread.
Original language | English (US) |
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Title of host publication | Encyclopedia of Virology |
Subtitle of host publication | Volume 1-5, Fourth Edition |
Publisher | Elsevier |
Pages | 899-909 |
Number of pages | 11 |
Volume | 1-5 |
ISBN (Electronic) | 9780128145166 |
DOIs | |
State | Published - Jan 1 2020 |
Keywords
- Antibody-dependent enhancement
- Arbovirus
- Congenital Zika syndrome
- Enzootic
- Flavivirus
- Guillain-Barré syndrome
- Microcephaly
- Pathogenesis
- Sexual transmission
- Sylvatic transmission cycle
- Urban transmission cycle
- Zika virus
ASJC Scopus subject areas
- General Immunology and Microbiology