Zinc and micronutrient repletion of children

Harold H. Sandstead, James G. Penland, Chen Xu-Cun, Ananda S. Prasad, Nancy W. Alcock, Norman G. Egger, Richard Carroll, Hari H. Dayal

Research output: Contribution to journalArticlepeer-review


Three studies measured effects of zinc repletion on growth and cognition of 6-9 year-old children. The first two involved urban and rural low-income Chinese children. The third was done on low income Mexican-Americans. Zinc repletion, given with other potentially limiting micronutrients for 10 weeks improved growth and cognition. The third study also measured immune functions. Zinc given with micronutrients increased IL-2 production and decreased IL-10 production by cultured peripheral blood mononuclear lymphocytes following phytohemaglutinin stimulation. Micronutrients alone had no apparent effect.

Original languageEnglish (US)
Pages (from-to)523-527
Number of pages5
JournalJournal of Trace and Microprobe Techniques
Issue number4
StatePublished - Nov 2000
Externally publishedYes


  • Behavior
  • Children
  • Growth
  • Human nutrition
  • Immunity
  • Zinc

ASJC Scopus subject areas

  • Analytical Chemistry


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